Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | EPOR | P19235 | 5/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.34 |
| ▸ | CHRNG | P07510 | 2/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.34 |
| ▸ | CHRND | Q07001 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP7 | P09237 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667809 | 0.94 | SMN1; SMN2 (0.38) | SMN1; SMN2EPORAVPR1BHPGDMEN1 | |
| SCHEMBL6889607 | 0.89 | SMN1; SMN2 (0.35) | SMN1; SMN2EPORAVPR1BHPGDMEN1 | |
| SCHEMBL4957686 | 0.86 | MMP2 (0.46) | SMN1; SMN2HPGDMEN1KMT2AMMP2 | |
| SCHEMBL7676093 | 0.85 | SMN1; SMN2 (0.34) | SMN1; SMN2EPORAVPR1BHPGDMEN1 | |
| SCHEMBL14271452 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2EPORHPGDMEN1KMT2A | |
| SCHEMBL4653743 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2EPORHPGDMEN1KMT2A | |
| SCHEMBL19809645 | 0.81 | MMP2 (0.47) | HPGDTAAR1MMP2MMP9MMP1 | |
| SCHEMBL4960020 | 0.81 | MMP2 (0.47) | HPGDTAAR1MMP2MMP9MMP1 | |
| Trifluoroacetic Acid SCHEMBL4385494 | 0.78 | ITGB3 (0.44) | HPGDTAAR1MMP2MMP9MMP1 | |
| Trifluoroacetic Acid SCHEMBL27589878 | 0.78 | ITGB3 (0.44) | HPGDTAAR1MMP2MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683163-B2 | MONITORING ANGIOGENESIS FACTOR | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-01-27 | — | — | US | disclosed |