SCHEMBL6889611

SCHEMBL6889611

COC(=O)c1ccc(CNc2cccc3ccccc23)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.58
KMT2A Q03164 4/20 0.58
MEN1 O00255 3/20 0.58
ALDH1A1 P00352 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
MAPT P10636 1/20 0.58
HPGD P15428 1/20 0.58
CA1 P00915 3/20 0.57
CA2 P00918 3/20 0.57
HDAC6 Q9UBN7 3/20 0.51
LOXL2 Q9Y4K0 1/20 0.50
TAOK1 Q7L7X3 1/20 0.49
POLB P06746 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
GSK3B P49841 1/20 0.49
CA12 O43570 1/20 0.49
CA4 P22748 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8587056 0.85 CA1 (0.57) KDM4EKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL19631309 0.85 HDAC6 (0.73) CA1CA2HDAC6LOXL2MAPK8
SCHEMBL19631406 0.85 HDAC6 (0.73) KDM4EALDH1A1SMN1; SMN2MAPTHDAC6
SCHEMBL19631484 0.84 HDAC6 (0.72) KDM4EKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL15459228 0.82 ALDH1A1 (0.75) KDM4EKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL15761734 0.81 CA1 (0.61) KMT2AMEN1ALDH1A1SMN1; SMN2MAPT
SCHEMBL19616918 0.81 HDAC6 (0.72) KMT2AMEN1ALDH1A1SMN1; SMN2CA1
SCHEMBL12309908 0.81 KDM4E (0.69) KDM4EKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL15761732 0.80 CA1 (0.60) KDM4EKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL15761720 0.80 CA1 (0.60) KMT2AMEN1ALDH1A1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6766183-B2 IMPLANTABLE BIOSENSOR; DETECTING AND MEASURING IN VIVO GLUCOSE CONCENTRATIONS MEDTRONIC MINIMED, INC. 2004-07-20 US disclosed
US-20020193672-A1 Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers LAWRENCE LIVERMORE NATIONAL SECURITY, LLC 2002-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193672-A1 Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers INSR, IRS1, IGF2R KDM4E 3433/4885KMT2A 3540/4885MEN1 1738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.