Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | MMP13 | P45452 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892026 | 1.00 | L3MBTL1 (0.76) | L3MBTL1POLBMMP13LMNAKMT2A | |
| SCHEMBL14679126 | 0.98 | L3MBTL1 (0.73) | L3MBTL1POLBMMP13LMNAKMT2A | |
| SCHEMBL6207746 | 0.93 | L3MBTL1 (0.70) | L3MBTL1POLBMMP13LMNAKMT2A | |
| SCHEMBL9489979 | 0.93 | L3MBTL1 (0.86) | L3MBTL1POLBMMP13LMNAKMT2A | |
| SCHEMBL29833827 | 0.91 | POLB (0.74) | L3MBTL1POLBNPC1RAB9AMAPK1 | |
| SCHEMBL24220267 | 0.86 | L3MBTL1 (1.00) | L3MBTL1POLBLMNAKMT2AMEN1 | |
| SCHEMBL7961787 | 0.86 | L3MBTL1 (1.00) | L3MBTL1POLBLMNAKMT2AMEN1 | |
| SCHEMBL8208835 | 0.86 | L3MBTL1 (1.00) | L3MBTL1POLBLMNAKMT2AMEN1 | |
| SCHEMBL764574 | 0.85 | MMP13 (0.81) | L3MBTL1POLBMMP13LMNAKMT2A | |
| SCHEMBL11966134 | 0.85 | L3MBTL1 (0.73) | L3MBTL1POLBMMP13LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014168-A1 | Reagents and methods for library synthesis and screening | HOWARD HUGHES MEDICAL INSTITUTE | 2004-01-22 | — | — | US | disclosed |