Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689685 | 1.00 | KMT2A (0.48) | KMT2AMEN1ESR1ESR2ELANE | |
| SCHEMBL688963 | 1.00 | KMT2A (0.48) | KMT2AMEN1ESR1ESR2ELANE | |
| SCHEMBL27705569 | 0.91 | MAPT (0.53) | KMT2AMEN1ESR1ESR2ELANE | |
| SCHEMBL11213281 | 0.91 | MAPT (0.53) | KMT2AMEN1ESR1ESR2ELANE | |
| SCHEMBL7459980 | 0.89 | PARP10 (0.46) | KMT2AMEN1ESR1ESR2ELANE | |
| SCHEMBL5176450 | 0.87 | ELANE (0.46) | KMT2AMEN1ESR1ESR2ELANE | |
| SCHEMBL10694037 | 0.87 | ELANE (0.46) | KMT2AMEN1ESR1ESR2ELANE | |
| SCHEMBL29009143 | 0.85 | CA12 (0.67) | KMT2AMEN1ESR1ESR2MAPT | |
| SCHEMBL5012588 | 0.83 | ELANE (0.40) | KMT2AMEN1ESR1ESR2ELANE | |
| SCHEMBL8858845 | 0.83 | KMT2A (0.46) | KMT2AMEN1ESR1ESR2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9464183-B2 | Rubber composition and pneumatic tire using the same | BRIDGESTONE CORPORATION (JP) | 2016-10-11 | — | — | US | disclosed |
| US-8222446-B2 | Method for producing dihydroxybenzene derivative | MITSUI CHEMICALS, INC. (JP) | 2012-07-17 | — | — | US | disclosed |
| EP-1820667-B1 | PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2012-02-29 | — | — | EP | disclosed |
| EP-1724302-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-20110146886-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |
| US-20110004013-A1 | METHOD FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE | MITSUI CHEMICALS, INC. (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2269976-A1 | PROCESS FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE | Mitsui Chemicals, Inc. (JP) | 2011-01-05 | — | — | EP | disclosed |
| US-7823614-B2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2010-11-02 | — | — | US | disclosed |
| US-20090229728-A1 | PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| US-20080047650-A1 | Rubber Composition And Pneumatic Tire Using The Same | BRIDGESTONE CORPORATION (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1820667-A1 | PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2007-08-22 | — | — | EP | disclosed |
| EP-1724252-A1 | COMPOUND AND COMPOSITION CONTAINING THE SAME | Mitsui Chemicals, Inc. (JP) | 2006-11-22 | — | — | EP | disclosed |
| EP-1724302-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME | Bridgestone Corporation (JP) | 2006-11-22 | — | — | EP | disclosed |
| US-20060205971-A1 | Compound and composition containing the same | MITSUI CHEMICALS, INC. (JP) | 2006-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205971-A1 | Compound and composition containing the same | RFC4, RFC5, RFC1 | KMT2A 1603/4885MEN1 1641/4885ESR1 804/4885 |
| US-20110004013-A1 | METHOD FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE | UBE2B, UBE2G2, TUBB2B | KMT2A 1007/4885MEN1 4103/4885ESR1 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.