SCHEMBL8858845

SCHEMBL8858845

O=CC(=O)Oc1ccc(O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
MEN1 O00255 1/20 0.46
ELANE P08246 3/20 0.46
GAA P10253 3/20 0.44
MAPT P10636 2/20 0.44
XBP1 P17861 1/20 0.44
KDM4E B2RXH2 1/20 0.43
GLA P06280 1/20 0.43
THRB P10828 1/20 0.43
BLM P54132 1/20 0.43
CASP6 P55212 1/20 0.43
GFER P55789 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH5A1 P51649 1/20 0.42
ABAT P80404 1/20 0.42
PARP10 Q53GL7 1/20 0.42
P4HB P07237 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11291636 0.98 ELANE (0.46) KMT2AESR1ESR2MEN1ELANE
SCHEMBL688964 0.83 KMT2A (0.48) KMT2AESR1ESR2MEN1ELANE
SCHEMBL688963 0.83 KMT2A (0.48) KMT2AESR1ESR2MEN1ELANE
SCHEMBL689685 0.83 KMT2A (0.48) KMT2AESR1ESR2MEN1ELANE
SCHEMBL140760 0.79 THRB (0.56) KMT2AESR1ESR2MEN1ELANE
SCHEMBL6741501 0.79 CYP11B1 (0.47) KMT2AMEN1ELANEMAPTHTT
SCHEMBL3976540 0.79 KMT2A (0.50) KMT2AMEN1GAAKDM4ECA1
SCHEMBL2129488 0.79 LMNA (0.61) KMT2AMEN1GAATDP1HTT
SCHEMBL28744273 0.79 LDHA (0.45) KMT2AMEN1MAPTCA1CA2
SCHEMBL7523578 0.79 MEN1 (0.50) KMT2AESR1ESR2MEN1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0315786-A1 Process for the preparation of a d-alfa-amino acid from the corresponding alfa-keto acid STAMICARBON B.V. (NL) 1989-05-17 EP claimed
CN-115851645-A Proteobacterium vulgaris meso-diaminopimelate dehydrogenase mutant and application thereof 江南大学 2023-03-28 CN disclosed
CN-115702223-A Phenolic resin and coating composition using the same PPG工业俄亥俄公司 2023-02-14 CN disclosed
WO-2019135987-A1 POLYCARBONATE DIOL COATING COMPOSITION FOR CAUSTIC AND UV RESISTANCE FERRO CORPORATION (US) 2019-07-11 WO disclosed
US-20190202733-A1 Polycarbonate Diol Coating Composition For Caustic And UV Resistance CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH, AS ADMINISTRATIVE AGENT 2019-07-04 US disclosed
CN-104093831-A Mbth-like proteins in the production of semi synthetic antibiotics DSM SINOCHEM PHARM NL BV 2014-10-08 CN disclosed
CN-101631853-B Production of beta-lactam antibiotics DSM IP ASSETS BV 2013-04-24 CN disclosed
CN-1040541-C Polypeptide compound and process for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1998-11-04 CN disclosed
WO-1997000678-A1 METHODS RELATED TO THE TREATMENT OF AND ISOLATION OF COMPOUNDS FOR TREATMENT OF ISCHAEMIC CONDITIONS THE QUEEN ELIZABETH HOSPITAL (AU) 1997-01-09 WO disclosed
EP-0385053-B1 Method for production of linoleum MONDO SPA (IT) 1994-07-27 EP disclosed
CN-1059729-A Novel polypeptide compound and preparation method thereof FUJISAWA PHARMACEUTICAL CO (JP) 1992-03-25 CN disclosed
EP-0385053-A2 Method for production of linoleum MONDO S.p.A. (IT) 1990-09-05 EP disclosed
EP-0315786-A1 Process for the preparation of a d-alfa-amino acid from the corresponding alfa-keto acid STAMICARBON B.V. (NL) 1989-05-17 EP disclosed
US-4699727-A POLYOXYALKYLENE POLYETHERS INITIATED WITH BISPHENOLS; NONSMOKING, ANTISLUDGING BASF CORPORATION (US) 1987-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202733-A1 Polycarbonate Diol Coating Composition For Caustic And UV Resistance DHCR24, ADH1C, ACMSD KMT2A 2369/4885ESR1 3667/4885ESR2 3324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.