Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516285 | 0.91 | PTGS2 (0.42) | PTGS2PTGS1F10 | |
| SCHEMBL6513081 | 0.83 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL6891068 | 0.78 | PTGS2 (0.38) | PTGS2PTGS1F10 | |
| SCHEMBL6894647 | 0.74 | PTGS2 (0.43) | PTGS2PTGS1F10 | |
| SCHEMBL6512653 | 0.72 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL7863025 | 0.71 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL6728836 | 0.71 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL6513264 | 0.70 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL6511509 | 0.70 | PTGS2 (0.40) | PTGS2PTGS1F10 | |
| SCHEMBL6514245 | 0.69 | PTGS2 (0.53) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157824-A1 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | PFIZER INC. | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157824-A1 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | CNR1, PTGS1, PTGER1 | PTGS2 29/4885PTGS1 2/4885F10 3660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.