Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.38 |
| ▸ | IKBKB | O14920 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055568 | 0.81 | BCAT2 (0.46) | IKBKB | |
| Hydrochloric Acid SCHEMBL5377283 | 0.78 | MKNK1 (0.51) | BTKKMT2A | |
| SCHEMBL3352707 | 0.77 | ALDH1A1 (0.41) | MAPTMEN1KMT2AHSD17B10USP2 | |
| SCHEMBL28525528 | 0.74 | BTK (0.44) | BTKMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL3350744 | 0.73 | HPGD (0.37) | MEN1KMT2AHSD17B10CHEK2ALDH1A1 | |
| SCHEMBL3356756 | 0.73 | STING1 (0.38) | CSNK1DCSNK1E | |
| SCHEMBL20453825 | 0.73 | BTK (0.41) | BTKMAPTMEN1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL3349083 | 0.72 | HPGD (0.36) | MEN1KMT2AHSD17B10CHEK2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3351578 | 0.72 | HPGD (0.36) | MEN1KMT2AHSD17B10CHEK2ALDH1A1 | |
| SCHEMBL3355465 | 0.72 | KDM4E (0.39) | MAPTMEN1KMT2AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |