Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 7/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 7/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061616 | 1.00 | GNAI3 (0.40) | GNAI3GNAO1GNAI1TSHRTHRB | |
| SCHEMBL6561478 | 1.00 | GNAI3 (0.40) | GNAI3GNAO1GNAI1TSHRTHRB | |
| SCHEMBL3661326 | 0.98 | GNAI3 (0.38) | GNAI3GNAO1GNAI1 | |
| SCHEMBL8512227 | 0.92 | GNAI3 (0.32) | GNAI3GNAO1GNAI1 | |
| SCHEMBL8160090 | 0.86 | GNAO1 (0.43) | GNAI3GNAO1GNAI1 | |
| SCHEMBL11597294 | 0.81 | — | — | |
| SCHEMBL11595655 | 0.78 | — | — | |
| SCHEMBL3513744 | 0.76 | — | — | |
| SCHEMBL11594967 | 0.76 | — | — | |
| SCHEMBL727413 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743956-A4 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORP (US) | 1999-03-24 | — | — | EP | claimed |
| EP-0743956-A1 | PRETARGETING METHODS AND COMPOUNDS | NeoRx (US) | 1996-11-27 | — | — | EP | claimed |
| EP-0906015-A4 | LIVER RETENTION CLEARING AGENTS | NEORX CORP (US) | 2004-05-12 | — | — | EP | disclosed |
| EP-0914042-A4 | CLUSTER CLEARING AGENTS | NEORX CORP (US) | 2000-10-25 | — | — | EP | disclosed |
| EP-0794788-A4 | HEPATIC-DIRECTED COMPOUNDS AND REAGENTS FOR PREPARATION THEREOF | NEORX CORP (US) | 2000-05-24 | — | — | EP | disclosed |
| EP-0914042-A1 | CLUSTER CLEARING AGENTS | NEORX CORPORATION (US) | 1999-05-12 | — | — | EP | disclosed |
| EP-0906015-A1 | LIVER RETENTION CLEARING AGENTS | NEORX CORPORATION (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0743956-A4 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| WO-1997046098-A9 | CLUSTER CLEARING AGENTS | — | 1998-08-06 | — | — | WO | disclosed |
| WO-1997046099-A1 | LIVER RETENTION CLEARING AGENTS | NEORX CORPORATION (US) | 1997-12-11 | — | — | WO | disclosed |
| WO-1997046098-A1 | CLUSTER CLEARING AGENTS | NEORX CORPORATION (US) | 1997-12-11 | — | — | WO | disclosed |
| EP-0794788-A1 | HEPATIC-DIRECTED COMPOUNDS AND REAGENTS FOR PREPARATION THEREOF | NEORX CORPORATION (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0743956-A1 | PRETARGETING METHODS AND COMPOUNDS | NeoRx (US) | 1996-11-27 | — | — | EP | disclosed |
| WO-1996017613-A1 | HEPATIC-DIRECTED COMPOUNDS AND REAGENTS FOR PREPARATION THEREOF | NEORX CORPORATION (US) | 1996-06-13 | — | — | WO | disclosed |