Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK10 | O94804 | 1/20 | 0.35 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888729 | 0.92 | BCHE (0.32) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL6888923 | 0.90 | STK10 (0.33) | STK10SLKCHEK1PIK3CALMNA | |
| SCHEMBL6889466 | 0.85 | LPAR5 (0.30) | — | |
| SCHEMBL5101461 | 0.84 | MEN1 (0.33) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL6888011 | 0.84 | STK10 (0.34) | STK10SLKPIK3CALMNAALDH1A1 | |
| SCHEMBL13880288 | 0.83 | STK10 (0.36) | STK10SLKCHEK1PIK3CALMNA | |
| SCHEMBL25838234 | 0.82 | CHEK1 (0.34) | STK10SLKCHEK1PIK3CALMNA | |
| SCHEMBL11995963 | 0.81 | PIK3CA (0.35) | STK10SLKPIK3CALMNAALDH1A1 | |
| SCHEMBL25605060 | 0.81 | PIK3CA (0.35) | STK10SLKPIK3CALMNAALDH1A1 | |
| SCHEMBL25716431 | 0.79 | PIK3CA (0.34) | STK10SLKPIK3CALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686468-B2 | FOR USE IN SYNTHETIC RESINS TO OBTAIN VIOLET TO BLUE TINTS; USED IN PHOTOTROPIC GLASSES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2004-02-03 | — | — | US | claimed |
| EP-1235823-B1 | H-ANNELLATED BENZO [F]CHROMENES | RODENSTOCK OPTIK G (DE) | 2003-07-16 | — | — | EP | claimed |
| US-20030040623-A1 | For use in synthetic resins to obtain violet to blue tints; used in phototropic glasses | RODENSTOCK GMBH (DE) | 2003-02-27 | — | — | US | claimed |
| US-6686468-B2 | FOR USE IN SYNTHETIC RESINS TO OBTAIN VIOLET TO BLUE TINTS; USED IN PHOTOTROPIC GLASSES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2004-02-03 | — | — | US | disclosed |
| EP-1235823-B1 | H-ANNELLATED BENZO [F]CHROMENES | RODENSTOCK OPTIK G (DE) | 2003-07-16 | — | — | EP | disclosed |
| US-20030040623-A1 | For use in synthetic resins to obtain violet to blue tints; used in phototropic glasses | RODENSTOCK GMBH (DE) | 2003-02-27 | — | — | US | disclosed |
| EP-1235823-A1 | H-ANNELLATED BENZO F]CHROMENES | Optische Werke G. Rodenstock (DE) | 2002-09-04 | — | — | EP | disclosed |
| WO-2002022594-A1 | H-ANNELLATED BENZO[F]CHROMENES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040623-A1 | For use in synthetic resins to obtain violet to blue tints; used in phototropic glasses | NR2E3, RB1, BRD7 | STK10 2370/4885SLK 3046/4885CHEK1 3151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.