SCHEMBL6889466

SCHEMBL6889466

COc1cc2c3c(c4c(c2cc1N1CCCCC1)-c1ccccc1C4)OC(c1ccccc1)(c1ccc(N(C)C)cc1)C=C3

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LPAR5 Q9H1C0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6888729 0.93 BCHE (0.32)
SCHEMBL6890929 0.85 STK10 (0.35)
SCHEMBL6889478 0.85
SCHEMBL5101461 0.83 MEN1 (0.33)
SCHEMBL6886646 0.80 TDP1 (0.32)
SCHEMBL6888923 0.80 STK10 (0.33)
SCHEMBL6889518 0.79 BCHE (0.32)
SCHEMBL13766140 0.77 DRD2 (0.36)
SCHEMBL21877240 0.74 MAPT (0.35)
SCHEMBL7792739 0.74 CA1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1235823-B1 H-ANNELLATED BENZO [F]CHROMENES RODENSTOCK OPTIK G (DE) 2003-07-16 EP claimed
US-20030040623-A1 For use in synthetic resins to obtain violet to blue tints; used in phototropic glasses RODENSTOCK GMBH (DE) 2003-02-27 US claimed
US-6686468-B2 FOR USE IN SYNTHETIC RESINS TO OBTAIN VIOLET TO BLUE TINTS; USED IN PHOTOTROPIC GLASSES OPTISCHE WERKE G. RODENSTOCK (DE) 2004-02-03 US disclosed
EP-1235823-B1 H-ANNELLATED BENZO [F]CHROMENES RODENSTOCK OPTIK G (DE) 2003-07-16 EP disclosed
US-20030040623-A1 For use in synthetic resins to obtain violet to blue tints; used in phototropic glasses RODENSTOCK GMBH (DE) 2003-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030040623-A1 For use in synthetic resins to obtain violet to blue tints; used in phototropic glasses NR2E3, RB1, BRD7 LPAR5 4021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.