SCHEMBL6891019

SCHEMBL6891019

Cc1cn([C@H]2C[C@H](O)[C@@H](COC(=O)OCC(C)c3ccc(I)cc3[N+](=O)[O-])O2)c(=O)[nH]c1=O

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.45
TYMS P04818 1/20 0.44
BCHE P06276 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7262901 1.00 POLB (0.45) POLBTYMSBCHE
SCHEMBL13666506 0.94 POLB (0.45) POLBTYMSBCHE
SCHEMBL6833513 0.94 POLB (0.45) POLBTYMSBCHE
SCHEMBL6833515 0.94 POLB (0.45) POLBTYMSBCHE
SCHEMBL13666503 0.91 POLB (0.45) POLBTYMS
SCHEMBL6892652 0.91 POLB (0.45) POLBTYMS
SCHEMBL7263516 0.91 POLB (0.45) POLBTYMS
SCHEMBL13666501 0.90 POLB (0.47) POLBTYMSBCHE
SCHEMBL6891978 0.90 POLB (0.47) POLBTYMSBCHE
SCHEMBL2521252 0.90 POLB (0.47) POLBTYMSBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1159064-B1 METHOD FOR PHOTOLYTICALLY DEPROTECTING IMMOBILIZED NUCLEOSIDE DERIVATIVES, ESPECIALLY IN THE PRODUCTION OF DNA CHIPS NIGU CHEMIE GMBH (DE) 2004-04-28 EP disclosed
EP-1159064-A1 METHOD FOR PHOTOLYTICALLY DEPROTECTING IMMOBILIZED NUCLEOSIDE DERIVATIVES, ESPECIALLY IN THE PRODUCTION OF DNA CHIPS NIGU CHEMIE GMBH (DE) 2001-12-05 EP disclosed
WO-2000053309-A1 METHOD FOR PHOTOLYTICALLY DEPROTECTING IMMOBILIZED NUCLEOSIDE DERIVATIVES, ESPECIALLY IN THE PRODUCTION OF DNA CHIPS NIGU CHEMIE GMBH (DE) 2000-09-14 WO disclosed