SCHEMBL6892652

SCHEMBL6892652

Cc1cn([C@H]2C[C@H](O)[C@@H](COC(=O)OCC(C)c3ccc(Br)cc3[N+](=O)[O-])O2)c(=O)[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.45
TYMS P04818 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13666503 1.00 POLB (0.45) POLBTYMS
SCHEMBL7263516 1.00 POLB (0.45) POLBTYMS
SCHEMBL6835970 0.94 POLB (0.45) POLBTYMS
SCHEMBL6835969 0.94 POLB (0.45) POLBTYMS
SCHEMBL13666505 0.94 POLB (0.45) POLBTYMS
SCHEMBL7262901 0.91 POLB (0.45) POLBTYMS
SCHEMBL6891019 0.91 POLB (0.45) POLBTYMS
SCHEMBL13666501 0.90 POLB (0.47) POLBTYMS
SCHEMBL6891978 0.90 POLB (0.47) POLBTYMS
SCHEMBL2521252 0.90 POLB (0.47) POLBTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1159064-B1 METHOD FOR PHOTOLYTICALLY DEPROTECTING IMMOBILIZED NUCLEOSIDE DERIVATIVES, ESPECIALLY IN THE PRODUCTION OF DNA CHIPS NIGU CHEMIE GMBH (DE) 2004-04-28 EP disclosed
US-6552182-B2 Gel or viscous liquid of polymer compounds and water, water/ alcohol mixtures and polar aprotic solvents is coated on the nucleoside and irradiated NIGU CHEMIE GMBH (DE) 2003-04-22 US disclosed
US-20020053508-A1 Method for photolytically deprotecting immobilized nucleoside derivatives, especially in the production of DNA chips NIGU CHEMIE GMBH 2002-05-09 US disclosed
EP-1159064-A1 METHOD FOR PHOTOLYTICALLY DEPROTECTING IMMOBILIZED NUCLEOSIDE DERIVATIVES, ESPECIALLY IN THE PRODUCTION OF DNA CHIPS NIGU CHEMIE GMBH (DE) 2001-12-05 EP disclosed
WO-2000053309-A1 METHOD FOR PHOTOLYTICALLY DEPROTECTING IMMOBILIZED NUCLEOSIDE DERIVATIVES, ESPECIALLY IN THE PRODUCTION OF DNA CHIPS NIGU CHEMIE GMBH (DE) 2000-09-14 WO disclosed