SCHEMBL6891023

SCHEMBL6891023

CN(C)C(=O)[C@H]1CC[C@H](NC(=S)C(=O)Nc2cncc(Cl)c2)[C@H](NC(=O)O)C1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.38
F2 P00734 2/20 0.37
F5 P12259 1/20 0.37
PLAT P00750 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4955283 0.84 F10 (0.39) F10F2F5
SCHEMBL1504130 0.81 F10 (0.54) F10F2F5
SCHEMBL1503968 0.79 RAB9A (0.39) F10
SCHEMBL1503972 0.79 RAB9A (0.39) F10
SCHEMBL4954407 0.77 RAB9A (0.44) F10F2F5
SCHEMBL6891046 0.77 PRMT5 (0.31)
SCHEMBL13748337 0.76 F10 (0.39) F10F2F5
SCHEMBL2941002 0.76 F10 (0.43) F10F2F5
SCHEMBL1504053 0.76 F10 (0.43) F10F2F5
SCHEMBL12101125 0.75 F10 (0.38) F10F2F5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1415992-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-05-06 EP disclosed