Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 6/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 6/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955316 | 0.84 | KCNQ3 (0.36) | — | |
| SCHEMBL1504138 | 0.81 | L3MBTL1 (0.42) | MAPT | |
| SCHEMBL6891023 | 0.77 | F10 (0.38) | — | |
| SCHEMBL4954432 | 0.77 | RAB9A (0.43) | MAPTMEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL1504064 | 0.76 | GRM5 (0.38) | — | |
| SCHEMBL4267987 | 0.73 | RHOA (0.35) | MAPTMEN1KMT2A | |
| SCHEMBL1503995 | 0.72 | L3MBTL1 (0.44) | — | |
| SCHEMBL4265707 | 0.72 | VNN1 (0.30) | — | |
| SCHEMBL4955407 | 0.72 | GLS (0.33) | — | |
| SCHEMBL1504199 | 0.70 | TSHR (0.36) | MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1415992-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | EP | disclosed |