SCHEMBL6891132

SCHEMBL6891132

CC1(C)O[C@H]2[C@@H](O1)[C@@H](COCc1ccc(I)cc1)O[C@@H]1OC(C)(C)O[C@@H]12

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
CA2 P00918 2/20 0.47
CA1 P00915 1/20 0.47
CA9 Q16790 1/20 0.47
HPGD P15428 1/20 0.37
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
MAPK1 P28482 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
GLB1 P16278 1/20 0.32
CYP3A4 P08684 1/20 0.32
IDO1 P14902 1/20 0.32
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6890870 0.88 ALDH1A1 (0.50) ALDH1A1CA2CA1CA9HPGD
SCHEMBL6886894 0.87 ALDH1A1 (0.49) ALDH1A1CA2CA1CA9HPGD
SCHEMBL10819414 0.87 ALDH1A1 (0.60) ALDH1A1CA2CA1CA9HPGD
SCHEMBL19588714 0.87 ALDH1A1 (0.60) ALDH1A1CA2CA1CA9HPGD
SCHEMBL2614786 0.87 ALDH1A1 (0.60) ALDH1A1CA2CA1CA9HPGD
SCHEMBL2623390 0.87 ALDH1A1 (0.60) ALDH1A1CA2CA1CA9HPGD
SCHEMBL1130657 0.87 ALDH1A1 (0.60) ALDH1A1CA2CA1CA9HPGD
SCHEMBL6894635 0.81 ALDH1A1 (0.52) ALDH1A1CA2CA1CA9HPGD
SCHEMBL6895477 0.80 ALDH1A1 (0.43) ALDH1A1CA2CA1CA9HPGD
SCHEMBL6893633 0.79 ALDH1A1 (0.50) ALDH1A1CA2CA1CA9POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6693178-B2 HALOGENATED BENZYL ETHER GALACTOPYRANOSIDE, GLUCOPYRANOSIDE, RIBOFURANOSIDE OR XYLOFURANOSIDE DERIVATIVES; STABLE, EASILY REMOVED MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2004-02-17 US claimed
US-6693178-B2 HALOGENATED BENZYL ETHER GALACTOPYRANOSIDE, GLUCOPYRANOSIDE, RIBOFURANOSIDE OR XYLOFURANOSIDE DERIVATIVES; STABLE, EASILY REMOVED MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2004-02-17 US disclosed
US-6426421-B1 HALOGENATED BENZYL ETHER-BASED PROTECTING GROUPS FOR FUNCTIONAL GROUPS, OF ALCOHOLS, THIOLS, AMINES, CARBOXYLIC ACIDS, AND PHOSPHORIC ACIDS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2002-07-30 US disclosed