Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLB1 | P16278 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886894 | 0.88 | ALDH1A1 (0.49) | ALDH1A1CA2CA1CA9HPGD | |
| SCHEMBL6891132 | 0.88 | ALDH1A1 (0.49) | ALDH1A1CA2CA1CA9HPGD | |
| SCHEMBL1130657 | 0.88 | ALDH1A1 (0.60) | ALDH1A1CA2CA1CA9HPGD | |
| SCHEMBL2623390 | 0.88 | ALDH1A1 (0.60) | ALDH1A1CA2CA1CA9HPGD | |
| SCHEMBL10819414 | 0.88 | ALDH1A1 (0.60) | ALDH1A1CA2CA1CA9HPGD | |
| SCHEMBL2614786 | 0.88 | ALDH1A1 (0.60) | ALDH1A1CA2CA1CA9HPGD | |
| SCHEMBL19588714 | 0.88 | ALDH1A1 (0.60) | ALDH1A1CA2CA1CA9HPGD | |
| SCHEMBL6894635 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CA2CA1CA9HPGD | |
| SCHEMBL10951538 | 0.81 | IDO1 (0.41) | HPGDTRPV6GAAMAPK1NPSR1 | |
| SCHEMBL6895477 | 0.81 | ALDH1A1 (0.43) | ALDH1A1CA2CA1CA9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693178-B2 | HALOGENATED BENZYL ETHER GALACTOPYRANOSIDE, GLUCOPYRANOSIDE, RIBOFURANOSIDE OR XYLOFURANOSIDE DERIVATIVES; STABLE, EASILY REMOVED | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-02-17 | — | — | US | claimed |
| US-6693178-B2 | HALOGENATED BENZYL ETHER GALACTOPYRANOSIDE, GLUCOPYRANOSIDE, RIBOFURANOSIDE OR XYLOFURANOSIDE DERIVATIVES; STABLE, EASILY REMOVED | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-02-17 | — | — | US | disclosed |
| US-20030181690-A1 | Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-09-25 | — | — | US | disclosed |
| US-6426421-B1 | HALOGENATED BENZYL ETHER-BASED PROTECTING GROUPS FOR FUNCTIONAL GROUPS, OF ALCOHOLS, THIOLS, AMINES, CARBOXYLIC ACIDS, AND PHOSPHORIC ACIDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2002-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181690-A1 | Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries | FUT5, FUT6, UGCG | ALDH1A1 1137/4885CA2 1939/4885CA1 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.