Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5863604 | 0.98 | HTR7 (0.42) | HTR7DRD2DRD4DRD1DRD3 | |
| SCHEMBL5864349 | 0.94 | HTR7 (0.42) | HTR7DRD2DRD4DRD3USP2 | |
| SCHEMBL5864186 | 0.94 | DRD3 (0.41) | HTR7DRD2DRD4DRD1DRD3 | |
| SCHEMBL5864096 | 0.94 | HTR7 (0.43) | HTR7DRD2DRD4DRD1DRD3 | |
| SCHEMBL5864369 | 0.92 | HTR7 (0.42) | HTR7DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL5863554 | 0.92 | LMNA (0.43) | DRD2DRD4DRD1DRD3HTR2A | |
| SCHEMBL5863702 | 0.92 | DRD3 (0.42) | HTR7DRD2DRD4DRD1DRD3 | |
| SCHEMBL5863715 | 0.92 | LMNA (0.40) | HTR7DRD2DRD4DRD1DRD3 | |
| SCHEMBL5864136 | 0.92 | HTR7 (0.44) | HTR7DRD2DRD4DRD1DRD3 | |
| SCHEMBL5864091 | 0.91 | DRD1 (0.41) | HTR7DRD2DRD4DRD1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777414-B1 | INHIBITORS OF TRIGLYCERIDE BIOSYNTHESIS AND SECRETION OF APOLIPOPROTEIN B-CONTAINING LIPOPROTEINS; ARTERIOSCLEROTIC DISEASES; HYPERLIPIDEMIA | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| EP-1180514-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND BENAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2002-02-20 | — | — | EP | disclosed |