SCHEMBL6891824

SCHEMBL6891824

CCC(OCCO)(C(=O)O)c1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 3/20 0.38
HSD17B10 Q99714 3/20 0.38
MEN1 O00255 2/20 0.38
CYP1A2 P05177 1/20 0.38
GLA P06280 1/20 0.38
POLB P06746 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.37
PPARA Q07869 3/20 0.34
PPARG P37231 3/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PPARD Q03181 2/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6888874 0.83 ALDH1A1 (0.44) ALDH1A1HPGDKDM4EHSD17B10PPARA
SCHEMBL5527765 0.72 ALDH1A1 (0.44) ALDH1A1HPGDKMT2AKDM4EHSD17B10
SCHEMBL29291615 0.71 ALDH1A1 (0.44) ALDH1A1HPGDKMT2AKDM4EHSD17B10
SCHEMBL29214674 0.71 CHRM2 (0.40) ALDH1A1KMT2AKDM4EMEN1CYP1A2
Pyrene SCHEMBL4668494 0.69 ALDH1A1 (0.42) ALDH1A1HPGDKMT2AKDM4EHSD17B10
SCHEMBL15023884 0.69 ALDH1A1 (0.44) ALDH1A1HPGDKMT2AKDM4EHSD17B10
SCHEMBL8002868 0.67 ALDH1A1 (0.46) ALDH1A1HPGDKMT2AKDM4EHSD17B10
Pyrene SCHEMBL28884873 0.65 HPGD (0.54) ALDH1A1HPGDKMT2AKDM4EHSD17B10
SCHEMBL2396985 0.64 ALDH1A1 (0.50) ALDH1A1HPGDKMT2AKDM4EHSD17B10
SCHEMBL8064322 0.64 IDO1 (0.50) ALDH1A1HPGDKMT2AKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040062927-A1 FLUORINATED DENDRONS AND SELF-ORGANIZING ULTRAHIGH DENSITY NANOCYLINDER COMPOSITIONS TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE 2004-04-01 US disclosed