Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053021 | 0.92 | AGTR1 (0.55) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL17653793 | 0.91 | AGTR1 (0.54) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| Losartan SCHEMBL60 | 0.91 | AGTR1 (0.67) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| Losartan SCHEMBL6092394 | 0.91 | AGTR1 (0.67) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| Losartan SCHEMBL29383742 | 0.91 | AGTR1 (0.67) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| Losartan SCHEMBL42080 | 0.90 | AGTR1 (0.66) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| SCHEMBL1628706 | 0.90 | AGTR1 (0.60) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| Losartan SCHEMBL7420948 | 0.90 | AGTR1 (0.66) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| Losartan SCHEMBL17653794 | 0.90 | AGTR1 (0.66) | AGTR1AGTR2ABCC4ABCB11PDE3B | |
| Losartan SCHEMBL3216357 | 0.90 | AGTR1 (0.66) | AGTR1AGTR2ABCC4ABCB11PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040084867-A1 | Individualization of therapy with anticoagulants | XANTHUS LIFE SCIENCES, INC. | 2004-05-06 | — | — | US | disclosed |
| WO-2004003550-A2 | INDIVIDUALIZATION OF THERAPY WITH ANTICOAGULANTS | XANTHUS LIFE SCIENCES, INC. (US) | 2004-01-08 | — | — | WO | disclosed |