Sugi Predict

Sugi Predict / Compounds / SCHEMBL689215

SCHEMBL689215

SCHEMBL689215

COC(=O)c1[nH]ncc1[N+](=O)[O-]

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.60
▸ L3MBTL1 Q9Y468 1/20 0.60
▸ MAPT P10636 4/20 0.56
▸ SMN1; SMN2 Q16637 3/20 0.53
▸ MITF O75030 2/20 0.53
▸ KMT2A Q03164 2/20 0.53
▸ MEN1 O00255 1/20 0.53
▸ CGAS Q8N884 2/20 0.49
▸ NPC1 O15118 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ TSHR P16473 2/20 0.44
▸ KDM4E B2RXH2 2/20 0.42
▸ HPGD P15428 2/20 0.41
▸ KDM4C Q9H3R0 1/20 0.41
▸ MAPK1 P28482 2/20 0.40
▸ ABCC4 O15439 1/20 0.40
▸ PLIN1 O60240 1/20 0.40
▸ CACNA1F O60840 1/20 0.40
▸ GMNN O75496 1/20 0.40
▸ KCNK2 O95069 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12820656 0.83 ALDH1A1 (0.55) ALDH1A1L3MBTL1MAPTSMN1; SMN2MITF
SCHEMBL10076963 0.81 MAPT (0.56) ALDH1A1L3MBTL1MAPTSMN1; SMN2MITF
SCHEMBL24966042 0.80 ALDH1A1 (0.48) ALDH1A1L3MBTL1MAPTSMN1; SMN2MITF
SCHEMBL2760495 0.79 MAPT (0.62) ALDH1A1L3MBTL1MAPTSMN1; SMN2MITF
SCHEMBL11299675 0.77 MAPT (0.56) ALDH1A1L3MBTL1MAPTSMN1; SMN2MITF
SCHEMBL3116767 0.77 MAPT (0.56) ALDH1A1L3MBTL1MAPTSMN1; SMN2MITF
Hydrochloric Acid SCHEMBL11299680 0.77 MAPT (0.60) ALDH1A1L3MBTL1MAPTSMN1; SMN2MITF
SCHEMBL12763866 0.77 MAPT (0.47) ALDH1A1L3MBTL1MAPTSMN1; SMN2MITF
SCHEMBL13967144 0.77 ALDH1A1 (0.56) ALDH1A1L3MBTL1MAPTSMN1; SMN2MITF
SCHEMBL27147932 0.73 TSHR (0.56) ALDH1A1L3MBTL1MAPTSMN1; SMN2MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617799-B2 Pyrazolopyrimidinone compounds Orphagen Pharmaceuticals, Inc. (US) 2026-05-05 — — US disclosed
WO-2026088205-A1 INHIBITORS OF SERINE PALMITOYLTRANSFERASE INTONATION RESEARCH LABORATORIES PRIVATE LIMITED. (IN) 2026-04-30 — — WO disclosed
US-12485123-B2 1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists BRISTOL-MYERS SQUIBB COMPANY (US) 2025-12-02 — — US disclosed
US-20250325673-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2025-10-23 — — US disclosed
EP-4626423-A1 CDK INHIBITORS AND METHODS AND USE THEREOF Relay Therapeutics, Inc. (US) 2025-10-08 — — EP disclosed
EP-4618977-A1 LRRK2 INHIBITORS AND USES THEREOF Neuron23, Inc. (US) 2025-09-24 — — EP disclosed
EP-4613773-A2 IRAK DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-09-10 — — EP disclosed
US-12371430-B2 5-morpholin-4-yl-pyrazolo[4,3-b]pyridine derivatives MERCK PATENT GMBH (DE) 2025-07-29 — — US disclosed
EP-3731869-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2025-07-23 — — EP disclosed
WO-2025038863-A1 INDOLE AND PYRROLOYPYRIDINE DERIVATIVES AS GPR17 MODULATORS BIOGEN MA INC. (US) 2025-02-20 — — WO disclosed
CN-1976907-A Heterocyclic amide compound and use thereof as an MMP-13 inhibitor TAKEDA PHARMACEUTICAL (JP) 2007-06-06 — — CN disclosed
US-20070105890-A1 Novel condensed imidazole derivative DAINIPPON SUMITOMO PHARMA CO., LTD 2007-05-10 — — US disclosed
US-20070105890-A1 Novel condensed imidazole derivative DAINIPPON SUMITOMO PHARMA CO., LTD 2007-05-10 — — US disclosed
US-20070105890-A1 Novel condensed imidazole derivative DAINIPPON SUMITOMO PHARMA CO., LTD 2007-05-10 — — US disclosed
US-20070027166-A1 Pyrazolo pyrimidines useful as aurora kinase inhibitors SUNESIS PHARMACEUTICALS, INC. 2007-02-01 — — US disclosed
US-20070027166-A1 Pyrazolo pyrimidines useful as aurora kinase inhibitors SUNESIS PHARMACEUTICALS, INC. 2007-02-01 — — US disclosed
WO-2007013964-A1 PYRAZOLO PYRIMIDINES USEFUL AS AURORA KINASE INHIBITORS SUNESIS PHARMACEUTICALS, INC. (US) 2007-02-01 — — WO disclosed
EP-1740551-A1 HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF AS AN MMP-13 INHIBITOR Takeda Pharmaceutical Company Limited (JP) 2007-01-10 — — EP disclosed
EP-1690863-A1 NOVEL CONDENSED IMIDAZOLE DERIVATIVE Dainippon Sumitomo Pharma Co., Ltd. (JP) 2006-08-16 — — EP disclosed
WO-2005105760-A1 HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF AS AN MMP-13 INHIBITOR TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-11-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325673-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 ALDH1A1 2776/4885L3MBTL1 1394/4885MAPT 2459/4885
US-20070105890-A1 Novel condensed imidazole derivative DPP4, DPP7, DPP3 ALDH1A1 63/4885L3MBTL1 97/4885MAPT 4633/4885
US-12485123-B2 1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists TLR7, TLR1, TLR9 ALDH1A1 1590/4885L3MBTL1 2808/4885MAPT 3546/4885
US-20070027166-A1 Pyrazolo pyrimidines useful as aurora kinase inhibitors AURKA, AURKB, AURKC ALDH1A1 3764/4885L3MBTL1 1307/4885MAPT 1438/4885
US-12617799-B2 Pyrazolopyrimidinone compounds CYP2B6, CBR1, CYP2D6 ALDH1A1 975/4885L3MBTL1 4687/4885MAPT 4243/4885
US-12371430-B2 5-morpholin-4-yl-pyrazolo[4,3-b]pyridine derivatives ATR, CDK1, CDKN1A ALDH1A1 2340/4885L3MBTL1 591/4885MAPT 1789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.