Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672628 | 0.93 | KMT2A (0.37) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL6678774 | 0.83 | TP53 (0.36) | KMT2AMEN1MAPTKDM4EADAMTS5 | |
| SCHEMBL6679148 | 0.83 | KMT2A (0.37) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6678058 | 0.83 | LMNA (0.34) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL6672631 | 0.82 | MAPT (0.38) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL6892244 | 0.81 | MAPT (0.38) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL6673176 | 0.81 | GAA (0.39) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL6674879 | 0.80 | MAPT (0.39) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6673164 | 0.80 | PHGDH (0.31) | MAPTKDM4EALDH1A1CYP2C19 | |
| SCHEMBL7044224 | 0.78 | KMT2A (0.38) | KMT2AMEN1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683184-B2 | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2004-01-27 | — | — | US | disclosed |