Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672631 | 0.92 | MAPT (0.38) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6650199 | 0.86 | ALDH1A1 (0.51) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL7044224 | 0.83 | KMT2A (0.38) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6678066 | 0.82 | PHGDH (0.35) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6678777 | 0.82 | PHGDH (0.37) | MAPTKDM4EKMT2AGAAL3MBTL1 | |
| SCHEMBL6679154 | 0.82 | MAPT (0.41) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL6672628 | 0.81 | KMT2A (0.37) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6892239 | 0.81 | KMT2A (0.37) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL5394355 | 0.81 | MAPT (0.42) | MAPTKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL6673181 | 0.80 | MAPT (0.40) | MAPTKDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683184-B2 | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2004-01-27 | — | — | US | disclosed |