Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1302702 | 0.86 | KMT2A (0.64) | KMT2AMAPTKDM4EATMCYP19A1 | |
| SCHEMBL11265688 | 0.74 | MAPT (0.61) | KMT2AMAPTKDM4EATMCYP19A1 | |
| SCHEMBL11269216 | 0.72 | MAPT (0.64) | KMT2AMAPTKDM4EATMCYP19A1 | |
| SCHEMBL28015970 | 0.71 | ALDH1A1 (0.50) | MAPTATMPOLB | |
| SCHEMBL1032004 | 0.70 | KDM4E (0.62) | KMT2AKDM4EATMCYP19A1MEN1 | |
| SCHEMBL28176844 | 0.70 | KDM4E (0.62) | KMT2AKDM4EATMCYP19A1MEN1 | |
| SCHEMBL2403628 | 0.70 | ATM (0.61) | KMT2AMAPTKDM4EATMCYP19A1 | |
| SCHEMBL11440293 | 0.70 | MAPT (0.60) | KMT2AMAPTKDM4EATMCYP19A1 | |
| Hydrochloric Acid SCHEMBL10448977 | 0.69 | KDM4E (0.61) | KMT2AKDM4EATMCYP19A1MEN1 | |
| SCHEMBL31157848 | 0.69 | CYP19A1 (0.77) | KMT2AMAPTKDM4EATMCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |