Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.54 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | TK1 | P04183 | 2/20 | 0.45 |
| ▸ | TK2 | O00142 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892320 | 0.88 | RNASE1 (0.56) | RNASE1TOP2ATK1TK2LMNA | |
| SCHEMBL7642202 | 0.86 | RNASE1 (0.45) | RNASE1TOP2ATK1 | |
| SCHEMBL7034889 | 0.85 | RNASE1 (0.53) | RNASE1TOP2ATK1TK2LMNA | |
| SCHEMBL7034888 | 0.85 | RNASE1 (0.53) | RNASE1TOP2ATK1TK2LMNA | |
| SCHEMBL7759628 | 0.82 | RNASE1 (0.53) | RNASE1TK1TK2LMNATSHR | |
| SCHEMBL7031391 | 0.80 | RNASE1 (0.52) | RNASE1TOP2ATK1TK2 | |
| SCHEMBL7031388 | 0.80 | RNASE1 (0.52) | RNASE1TOP2ATK1TK2 | |
| SCHEMBL13284062 | 0.79 | RNASE1 (0.40) | RNASE1TOP2ATK1TK2LMNA | |
| SCHEMBL7648736 | 0.79 | RNASE1 (0.52) | RNASE1TK1TK2LMNATSHR | |
| SCHEMBL7644538 | 0.79 | RNASE1 (0.58) | RNASE1TK1TK2ALBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212338-B1 | Nucleoside derivatives with photolabile protective groups | DEUTSCHES KREBSFORSCH (DE) | 2012-11-21 | — | — | EP | disclosed |
| US-6756492-B1 | Nucleoside derivatives with photo-unstable protective groups | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUND DES OFFENTLICHEN RECHTS (DE) | 2004-06-29 | — | — | US | disclosed |