Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MASP2 | O00187 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 3/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3649450 | 0.90 | TACR1 (0.46) | LMNAMASP2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6895745 | 0.86 | LMNA (0.47) | LMNACYP1A2CYP2D6CYP2C19MEN1 | |
| SCHEMBL6894820 | 0.85 | CYP1A2 (0.60) | LMNACYP1A2CYP2D6CYP2C19NR3C2 | |
| SCHEMBL6890574 | 0.85 | PLA2G1B (0.52) | LMNAPNMTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3641583 | 0.84 | CYP1A2 (0.41) | LMNAMASP2CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL7112448 | 0.84 | MEN1 (0.43) | LMNACYP1A2CYP2D6CYP2C19IDO1 | |
| SCHEMBL165645 | 0.82 | CASR (0.57) | MEN1KMT2A | |
| SCHEMBL4307949 | 0.82 | KMT2A (0.40) | LMNAMEN1KMT2A | |
| SCHEMBL4692485 | 0.82 | CASR (0.57) | MEN1KMT2A | |
| SCHEMBL3645149 | 0.82 | BCHE (0.52) | TACR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |