Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | CCKBR | P32239 | 3/20 | 0.54 |
| ▸ | CDK4 | P11802 | 6/20 | 0.52 |
| ▸ | CCND1 | P24385 | 5/20 | 0.52 |
| ▸ | NMBR | P28336 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9086070 | 0.84 | KMT2A (0.56) | KMT2ATAAR1CCKBRCDK4 | |
| SCHEMBL9519964 | 0.82 | TACR1 (0.48) | CCKBR | |
| SCHEMBL6892425 | 0.81 | CCKBR (0.78) | CCKBRNMBR | |
| SCHEMBL27336638 | 0.80 | KMT2A (0.54) | KMT2ATAAR1CDK4CCND1CDK2 | |
| SCHEMBL9083273 | 0.79 | CCKBR (0.51) | CCKBR | |
| SCHEMBL10625743 | 0.78 | CCKBR (0.68) | CCKBRNMBR | |
| SCHEMBL8895086 | 0.78 | KMT2A (0.51) | KMT2ATAAR1CCKBR | |
| SCHEMBL8895076 | 0.78 | KMT2A (0.51) | KMT2ATAAR1CCKBR | |
| SCHEMBL8829876 | 0.76 | CCKBR (0.68) | KMT2ACCKBRNMBR | |
| SCHEMBL18701548 | 0.76 | CDK4 (0.68) | CDK4CCND1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492531-B1 | THE INVENTION CONCERNS CHOLECYSTOKININ (CCK) ANTAGONISTS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS. ESPECIALLY USEFUL ARE CCK.SUB.B ANTAGONISTS SUCH AS CI-988. | WARNER-LAMBERT COMPANY | 2002-12-10 | — | — | US | claimed |
| EP-0405537-B1 | N-substituted cycloalkyl and polycycloalkyl alpha-substituted Trp-Phe- and phenethylamine derivatives | WARNER LAMBERT CO (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6492531-B1 | THE INVENTION CONCERNS CHOLECYSTOKININ (CCK) ANTAGONISTS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS. ESPECIALLY USEFUL ARE CCK.SUB.B ANTAGONISTS SUCH AS CI-988. | WARNER-LAMBERT COMPANY | 2002-12-10 | — | — | US | disclosed |
| US-5631281-A | COMPOUNDS FOR TREATMENT OF ANXIETY WITH INDOLE AMIDES | WARNER-LAMBERT COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5622983-A | ANTIOBESITY AGENTS, ANTIPSYCHOTIC AGENTS, ANTIULCER AGENTS | WARNER-LAMBERT COMPANY (US) | 1997-04-22 | — | — | US | disclosed |
| US-5580896-A | Treatment of pain and colorectal cancer with dipeptoids of α-substituted Trp-Phe derivatives | WARNER-LAMBERT COMPANY (US) | 1996-12-03 | — | — | US | disclosed |
| US-5554643-A | Pro-drugs for CCK antagonists | WARNER-LAMBERT COMPANY (US) | 1996-09-10 | — | — | US | disclosed |
| US-5340825-A | Pro drugs for CCK antagonists | WARNER-LAMBERT COMPANY (US) | 1994-08-23 | — | — | US | disclosed |
| US-5318981-A | Unnatural dipeptoids of alpha-substituted tyrosine-phenylalanine derivatives | WARNER-LAMBERT COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| US-5278316-A | Indoles | WARNER-LAMBERT COMPANY (US) | 1994-01-11 | — | — | US | disclosed |
| US-5217957-A | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-06-08 | — | — | US | disclosed |
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |
| WO-1993000897-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL IN THE TREATMENT OF PANIC ATTACKS | WARNER-LAMBERT COMPANY (US) | 1993-01-21 | — | — | WO | disclosed |
| EP-0479910-A1 | N-SUBSTITUTED CYCLOALKYL AND POLYCYCLOALKYL ALPHA-SUBSTITUTED Trp-Phe- AND PHENETHYLAMINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1992-04-15 | — | — | EP | disclosed |
| WO-1992004038-A1 | PRO-DRUGS FOR CCK ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |
| WO-1991000274-A1 | N-SUBSTITUTED CYCLOALKYL AND POLYCYCLOALKYL ALPHA-SUBSTITUTED TRP-PHE- AND PHENETHYLAMINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1991-01-10 | — | — | WO | disclosed |
| EP-0405537-A1 | N-substituted cycloalkyl and polycycloalkyl alpha-substituted Trp-Phe- and phenethylamine derivatives | WARNER-LAMBERT COMPANY (US) | 1991-01-02 | — | — | EP | disclosed |