Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 9/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9086070 | 0.84 | KMT2A (0.56) | CCKBRMC4R | |
| SCHEMBL6892600 | 0.79 | KMT2A (0.55) | CCKBR | |
| SCHEMBL9832751 | 0.75 | CCKBR (0.47) | CCKBR | |
| SCHEMBL9832740 | 0.75 | CCKBR (0.47) | CCKBR | |
| SCHEMBL8892465 | 0.75 | KDM4E (0.49) | CCKBRNPC1SMN1; SMN2 | |
| SCHEMBL8892454 | 0.75 | KDM4E (0.49) | CCKBRNPC1SMN1; SMN2 | |
| SCHEMBL22835926 | 0.75 | NMBR (0.53) | CCKBRSMN1; SMN2 | |
| SCHEMBL10625743 | 0.74 | CCKBR (0.68) | CCKBR | |
| SCHEMBL8829876 | 0.74 | CCKBR (0.68) | CCKBRNPC1 | |
| Hexane SCHEMBL27913412 | 0.73 | SMN1; SMN2 (0.51) | MTNR1ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523306-A | TRYPTOPHAN DERIVATIVES FOR BLOCKING DRUG OR ALCOHOL WITHDRAWAL RESPONSE IN MAMMALS; ANTIPSYCHOTIC, ANTIULCER AGENTS; APPETITE SUPPRESSANTS | WARNER-LAMBERT COMPANY (US) | 1996-06-04 | — | — | US | disclosed |
| US-5397788-A | Antitumor agents, antiulcer agents, antipsychotics or anxiety | WARNER-LAMBERT COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0546123-A4 | — | — | 1994-04-27 | — | — | EP | disclosed |
| US-5244915-A | Anxiolytic agents, tryptophan dipeptide derivatives | WARNER-LAMBERT COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0546123-A1 | ALPHA-SUBSTITUTED TRYPTOPHANE DIPEPTOID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992004322-A1 | ALPHA-SUBSTITUTED TRYPTOPHANE DIPEPTOID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |