Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 17/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2402803 | 0.95 | CRHR1 (0.70) | CRHR1NPSR1HPGDMAPT | |
| Hydrochloric Acid SCHEMBL2403782 | 0.95 | CRHR1 (0.69) | CRHR1NPSR1HPGDMAPT | |
| SCHEMBL13139625 | 0.92 | CRHR1 (0.78) | CRHR1HPGDMAPTALDH1A1 | |
| SCHEMBL2404407 | 0.89 | CRHR1 (0.69) | CRHR1NPSR1HPGDMAPTALDH1A1 | |
| SCHEMBL2402995 | 0.88 | CRHR1 (0.84) | CRHR1 | |
| SCHEMBL2401787 | 0.87 | CRHR1 (0.77) | CRHR1 | |
| Hydrochloric Acid SCHEMBL2406976 | 0.87 | CRHR1 (0.82) | CRHR1 | |
| SCHEMBL2401226 | 0.86 | CRHR1 (0.79) | CRHR1NPSR1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL3608713 | 0.86 | CRHR1 (0.76) | CRHR1 | |
| SCHEMBL2402804 | 0.86 | CRHR1 (0.70) | CRHR1HPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040072833-A1 | Tricyclic and heterocyclic derivative compounds and drugs containing these compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-04-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072833-A1 | Tricyclic and heterocyclic derivative compounds and drugs containing these compounds as the active ingredient | CRH, CRHR1, CRHR2 | CRHR1 2/4885NPSR1 12/4885HPGD 738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.