Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxyamine SCHEMBL8060839 | 0.79 | CYP3A4 (0.36) | ACHE | |
| Dimethylamine SCHEMBL9066431 | 0.78 | ACHE (0.33) | ACHE | |
| SCHEMBL29040553 | 0.75 | ACHE (0.30) | ACHE | |
| Water SCHEMBL5062444 | 0.74 | — | — | |
| SCHEMBL29894137 | 0.74 | CHKA (0.32) | ACHE | |
| SCHEMBL30547267 | 0.74 | CHKA (0.32) | ACHE | |
| SCHEMBL30945595 | 0.74 | CHKA (0.32) | ACHE | |
| Ammonia Solution, Strong SCHEMBL3063865 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL27669855 | 0.73 | — | — | |
| SCHEMBL27572229 | 0.72 | DRD1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |