Methoxyamine

Methoxyamine

SCHEMBL8060839

CON.c1cc2cc(c1)C2

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.36
ALDH1A1 P00352 1/20 0.36
IDO1 P14902 4/20 0.34
AGXT P21549 2/20 0.34
ACHE P22303 2/20 0.32
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2E1 P05181 1/20 0.31
CYP2C8 P10632 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP4B1 P13584 1/20 0.31
CYP2B6 P20813 1/20 0.31
CYP3A5 P20815 1/20 0.31
CYP2A7 P20853 1/20 0.31
CYP3A7 P24462 1/20 0.31
CYP2F1 P24903 1/20 0.31
CYP2C18 P33260 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9520788 0.79
Hydroxyamine SCHEMBL8659777 0.79
SCHEMBL29040553 0.79 ACHE (0.30) ACHE
SCHEMBL6892878 0.79 ACHE (0.30) ACHE
SCHEMBL29894137 0.78 CHKA (0.32) CYP3A4ALDH1A1ACHECA2CA9
Ammonia Solution, Strong SCHEMBL3063865 0.78
SCHEMBL30945595 0.78 CHKA (0.32) CYP3A4ALDH1A1ACHECA2CA9
SCHEMBL30547267 0.78 CHKA (0.32) CYP3A4ALDH1A1ACHECA2CA9
Water SCHEMBL5062444 0.78
Hydrochloric Acid SCHEMBL27669855 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0674232-B1 Recording sheets XEROX CORP (US) 2000-05-31 EP claimed
EP-0593639-A1 PYRROLIDINE AND THIAZOLIDINE DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME. RHONE POULENC RORER SA (FR) 1994-04-27 EP disclosed
WO-1993001167-A1 PYRROLIDINE AND THIAZOLIDINE DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME RHONE-POULENC RORER S.A. (FR) 1993-01-21 WO disclosed
EP-0091385-B1 PROCESS FOR THE PREPARATION OF P-HYDROXYBENZYL NITRILES OR P-HYDROXYBENZYL AMINES RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-06-12 EP disclosed
EP-0091385-A1 Process for the preparation of p-hydroxybenzyl nitriles or p-hydroxybenzyl amines RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-10-12 EP disclosed