Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 7/20 | 0.47 |
| ▸ | FDPS | P14324 | 12/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28901725 | 0.88 | GGPS1 (0.47) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL7549125 | 0.76 | FDPS (0.55) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL7796960 | 0.76 | FDPS (0.55) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL4267775 | 0.71 | GGPS1 (0.59) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL5004323 | 0.71 | GGPS1 (0.59) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL9486308 | 0.71 | GGPS1 (0.59) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL11024893 | 0.70 | SMPD1 (0.56) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| SCHEMBL11021842 | 0.70 | SMPD1 (0.56) | GGPS1FDPSSMPD1LPAR1LPAR3 | |
| Glycerin SCHEMBL4966680 | 0.69 | KDM4E (0.46) | — | |
| SCHEMBL9487614 | 0.69 | GGPS1 (0.57) | GGPS1FDPSSMPD1LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792275-B1 | IMPROVED ANTIVIRAL PRODRUGS | UNIV CALIFORNIA (US) | 2004-03-03 | — | — | EP | disclosed |
| US-6002029-A | Antiviral prodrugs | CHIMERIX, INC. | 1999-12-14 | — | — | US | disclosed |
| US-5696277-A | CYTOMEGALOVIRUS, HERPES VIRUS | Hostetler, Karl Y. (US) | 1997-12-09 | — | — | US | disclosed |