Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 13/20 | 0.55 |
| ▸ | GGPS1 | O95749 | 8/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549125 | 1.00 | FDPS (0.55) | FDPSGGPS1SMPD1LPAR1LPAR3 | |
| SCHEMBL7554692 | 0.91 | GGPS1 (0.49) | FDPSGGPS1SMPD1LPAR1LPAR3 | |
| SCHEMBL4566606 | 0.85 | FDPS (0.56) | FDPSGGPS1SMPD1LPAR1LPAR3 | |
| SCHEMBL6535665 | 0.80 | LPAR5 (0.49) | FDPSGGPS1SMPD1LPAR1LPAR3 | |
| SCHEMBL4552690 | 0.77 | GGPS1 (0.48) | FDPSGGPS1SMPD1LPAR3 | |
| SCHEMBL4552171 | 0.77 | GGPS1 (0.48) | FDPSGGPS1SMPD1LPAR3 | |
| SCHEMBL27769203 | 0.77 | FDPS (0.34) | FDPSGGPS1PDE3A | |
| SCHEMBL28145287 | 0.77 | FDPS (0.34) | FDPSGGPS1PDE3A | |
| SCHEMBL6893055 | 0.76 | GGPS1 (0.47) | FDPSGGPS1SMPD1LPAR1LPAR3 | |
| SCHEMBL142854 | 0.74 | LMNA (0.41) | FDPSGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156797-A2 | SYNERGISTIC INHIBITION OF VIRAL REPLICATION BY LONG-CHAIN HYDROCARBONS AND NUCLEOSIDE ANALOGS | Avanir Pharmaceuticals (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000053167-A2 | SYNERGISTIC INHIBITION OF VIRAL REPLICATION BY LONG-CHAIN HYDROCARBONS AND NUCLEOSIDE ANALOGS | AVANIR PHARMACEUTICALS (US) | 2000-09-14 | — | — | WO | disclosed |