Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19362383 | 0.82 | SLC6A2 (0.34) | SIGMAR1SLC6A4SLC6A2GNAI3GNAO1 | |
| SCHEMBL3346527 | 0.79 | — | — | |
| SCHEMBL3815697 | 0.77 | SLC6A4 (0.41) | SIGMAR1SLC6A4SLC6A2GNAI3GNAO1 | |
| SCHEMBL11724424 | 0.77 | SIGMAR1 (0.37) | SIGMAR1SLC6A4SLC6A2GNAI3GNAO1 | |
| SCHEMBL9387362 | 0.77 | SLC6A3 (0.38) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6578962 | 0.76 | SIGMAR1 (0.36) | SIGMAR1SLC6A4SLC6A2GNAI3GNAO1 | |
| SCHEMBL7678645 | 0.76 | SIGMAR1 (0.36) | SIGMAR1SLC6A4SLC6A2GNAI3GNAO1 | |
| SCHEMBL3822012 | 0.76 | SIGMAR1 (0.36) | SIGMAR1SLC6A4SLC6A2GNAI3GNAO1 | |
| SCHEMBL12300812 | 0.76 | MC4R (0.36) | SLC6A3KCNH2CYP2D6 | |
| SCHEMBL23956553 | 0.74 | SLC6A4 (0.39) | SIGMAR1SLC6A4SLC6A2GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022554-A1 | QUINAZOLINONE DERIVATIVES | CELLTECH R & D LIMITED (GB) | 2004-03-18 | — | — | WO | disclosed |