Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 6/20 | 0.38 |
| ▸ | ACACA | Q13085 | 6/20 | 0.38 |
| ▸ | DPP4 | P27487 | 6/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6893180 | 0.87 | GRM2 (0.59) | PRMT5GRM2IRAK1 | |
| SCHEMBL6892790 | 0.75 | GRM2 (0.45) | GRM2DPP4 | |
| SCHEMBL6890927 | 0.74 | GRM2 (0.75) | GRM2 | |
| SCHEMBL6893152 | 0.74 | GRM2 (0.61) | GRM2DPP4 | |
| SCHEMBL6893856 | 0.74 | GRM2 (0.61) | GRM2DPP4 | |
| SCHEMBL6891956 | 0.73 | GRM2 (0.58) | GRM2 | |
| SCHEMBL15185173 | 0.73 | GRM2 (0.51) | GRM2ACACBACACA | |
| SCHEMBL6893516 | 0.73 | GRM2 (0.54) | GRM2 | |
| SCHEMBL6893000 | 0.72 | GRM2 (0.56) | PRMT5GRM2 | |
| Hydrochloric Acid SCHEMBL1502997 | 0.72 | GRM2 (0.54) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034741-A1 | IMIDAZOPYRIDIN-2-ONE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2011-03-24 | — | — | WO | disclosed |