Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 4/20 | 0.63 |
| ▸ | F2 | P00734 | 7/20 | 0.62 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.60 |
| ▸ | F10 | P00742 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.55 |
| ▸ | HPD | P32754 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19608215 | 0.91 | MRGPRX4 (0.60) | NR4A2MAOBF2SMPD1F10 | |
| SCHEMBL9586282 | 0.87 | NR4A2 (0.71) | NR4A2MAOBF2SMPD1SRD5A2 | |
| SCHEMBL7900723 | 0.84 | PRSS1 (0.54) | NR4A2F2 | |
| SCHEMBL8255981 | 0.84 | F2 (0.88) | NR4A2F2F10 | |
| SCHEMBL1387246 | 0.84 | NR4A2 (0.77) | NR4A2MAOBF2SMPD1F10 | |
| Hydrochloric Acid SCHEMBL23880704 | 0.83 | F2 (0.88) | NR4A2F2F10 | |
| Hydrochloric Acid SCHEMBL27603151 | 0.83 | NR4A2 (0.74) | NR4A2MAOBF2SMPD1F10 | |
| SCHEMBL7896958 | 0.82 | PRSS1 (0.55) | NR4A2F2 | |
| SCHEMBL6890765 | 0.81 | PARP10 (0.70) | NR4A2MAOBF2SRD5A2 | |
| SCHEMBL7889327 | 0.81 | PRSS1 (0.56) | NR4A2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104817553-B | The pyrimidinediamine class compound and its derivative and its medical usage of a kind of aromatic radical-heterocyclic substituted | 华东师范大学 | 2018-11-09 | — | — | CN | disclosed |
| CN-104817553-A | Aryl-heterocycle substituted pyrimidinediamine compound and its derivative and pharmaceutical use thereof | UNIV EAST CHINA NORMAL | 2015-08-05 | — | — | CN | disclosed |
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| US-6277998-B1 | REACTING 2-CYANO-4-OXO-4H-BENZOPYRAN COMPOUND WITH HYDROGEN SULFIDE AND THEN REACTING PROUDCT WITH ALKYL HALIDE; REACTING THE PRODUCT WITH HYDRAZINE OR ITS SALT AND THEN WITH NITROUS ACID COMPOUND TO OBTAIN TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-21 | — | — | US | disclosed |
| US-6191289-B1 | REACTING A 4-OXO-4H-BENZOPYRAN GROUP SUBSTITUTED WITH AMIDE OR A PHENYL GROUP IN ITS 2 POSITION IS REACTED WITH ANHYDROUS HYDRAZINE OR SALT IN PRESENCE OF CATALYST FOLLOWED BY REACTING WITH NITROUS ACID OR SALT TO FORM TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| US-5874593-A | SULFUR CONTAINING AMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |
| EP-0711762-A1 | PROCESS FOR PRODUCING TETRAZOLE COMPOUND AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |