Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.71 |
| ▸ | MAOB | P27338 | 4/20 | 0.67 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.58 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 3/20 | 0.57 |
| ▸ | HPD | P32754 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6893845 | 0.87 | NR4A2 (0.67) | NR4A2MAOBSMPD1SRD5A2PTPN1 | |
| SCHEMBL9586301 | 0.86 | NR4A2 (0.74) | NR4A2MAOBF2RAB9A | |
| SCHEMBL9585753 | 0.84 | FFAR1 (0.57) | NR4A2MAOBSMPD1F2 | |
| SCHEMBL7908051 | 0.83 | SRD5A2 (0.85) | NR4A2MAOBSMPD1SRD5A2PTPN1 | |
| SCHEMBL339009 | 0.83 | NR4A2 (1.00) | NR4A2MAOBSMPD1SRD5A2PTPN1 | |
| SCHEMBL30207018 | 0.83 | NR4A2 (1.00) | NR4A2MAOBSMPD1SRD5A2PTPN1 | |
| SCHEMBL3442746 | 0.81 | NR4A2 (0.79) | NR4A2MAOBSMPD1SRD5A2PTPN1 | |
| Hydrochloric Acid SCHEMBL4748074 | 0.81 | NR4A2 (0.97) | NR4A2MAOBSMPD1SRD5A2PTPN1 | |
| SCHEMBL1268719 | 0.81 | MAOB (0.81) | NR4A2MAOBSMPD1CYP4F2CYP4A11 | |
| SCHEMBL8255981 | 0.80 | F2 (0.88) | NR4A2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204482-A | Ethylenediamine monoamide heteroaryl derivatives | HOFFMAN-LAROCHE INC. (US) | 1993-04-20 | — | — | US | disclosed |
| US-5011849-A | Monoamine oxidase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1991-04-30 | — | — | US | disclosed |