Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.70 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897887 | 0.83 | NPC1 (0.62) | PARP10RAB9ANPC1MAOBMAOA | |
| SCHEMBL11119945 | 0.83 | NR4A2 (0.64) | PARP10NR4A2LMNARAB9ANPC1 | |
| SCHEMBL8558672 | 0.83 | NPC1 (0.64) | PARP10RAB9ANPC1MAOBMAPT | |
| SCHEMBL27604519 | 0.82 | MAOB (0.70) | PARP10NR4A1NR4A2NR4A3CYP1A2 | |
| SCHEMBL119689 | 0.82 | PARP10 (1.00) | PARP10NR4A1NR4A2NR4A3CYP1A2 | |
| SCHEMBL6629683 | 0.82 | F2 (0.83) | PARP10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL864192 | 0.81 | ALDH1A1 (0.60) | PARP10NR4A1NR4A2NR4A3CYP1A2 | |
| SCHEMBL6893845 | 0.81 | NR4A2 (0.67) | NR4A2MAOBSRD5A2F2 | |
| SCHEMBL28017864 | 0.81 | FFAR1 (0.56) | PARP10LMNARAB9ANPC1PLA2G4B | |
| SCHEMBL521489 | 0.81 | NR4A1 (0.72) | PARP10NR4A1NR4A2NR4A3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |
| CN-104817553-B | The pyrimidinediamine class compound and its derivative and its medical usage of a kind of aromatic radical-heterocyclic substituted | 华东师范大学 | 2018-11-09 | — | — | CN | disclosed |
| CN-103694195-B | Aromatic heterocyclic small molecular organic compounds and derivative, preparation method and medicinal use | EAST CHINA NORMAL UNIVERSITY (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-104817553-A | Aryl-heterocycle substituted pyrimidinediamine compound and its derivative and pharmaceutical use thereof | UNIV EAST CHINA NORMAL | 2015-08-05 | — | — | CN | disclosed |
| CN-103694195-A | Heterocyclic aromatic micromolecule organic compounds and derivatives, preparation method and medical application | UNIV EAST CHINA NORMAL | 2014-04-02 | — | — | CN | disclosed |
| US-6191289-B1 | REACTING A 4-OXO-4H-BENZOPYRAN GROUP SUBSTITUTED WITH AMIDE OR A PHENYL GROUP IN ITS 2 POSITION IS REACTED WITH ANHYDROUS HYDRAZINE OR SALT IN PRESENCE OF CATALYST FOLLOWED BY REACTING WITH NITROUS ACID OR SALT TO FORM TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | disclosed |
| US-5874593-A | SULFUR CONTAINING AMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |
| EP-0711762-A1 | PROCESS FOR PRODUCING TETRAZOLE COMPOUND AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |