Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.54 |
| ▸ | GABRD | O14764 | 2/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.54 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.54 |
| ▸ | GABRE | P78334 | 2/20 | 0.54 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.54 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.54 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.54 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.54 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | BHMT | Q93088 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898945 | 1.00 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18980511 | 0.98 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6666416 | 0.88 | ENPEP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6664634 | 0.88 | ENPEP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4000950 | 0.84 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3994890 | 0.84 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3994937 | 0.84 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4411760 | 0.84 | SLC1A3 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL288992 | 0.84 | SLC1A3 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28364576 | 0.82 | GABRR1 (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910362-B1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 2004-10-27 | — | — | EP | claimed |
| CN-1110302-C | Oxa acids and related compounds for treating skin conditions | AVON PROD INC (US) | 2003-06-04 | — | — | CN | claimed |
| US-6534543-B2 | Topical compositions with carboxy acid/ester, amide, or thioester/thioacid groups, with one or more of ether, amine, or sulfide groups; for example 3,6-dioxaheptanioic acid; peeling skin, softening hair | AVON PRODUCTS, INC. | 2003-03-18 | — | — | US | claimed |
| US-20020040056-A1 | Oxa acids and related compounds for treating skin conditions | AVON PRODUCTS, INC. | 2002-04-04 | — | — | US | claimed |
| JP-2000511900-A | — | — | 2000-09-12 | — | — | JP | claimed |
| EP-0910362-A4 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 1999-12-22 | — | — | EP | claimed |
| CN-1221342-A | Oxo acids and related compounds for the treatment of skin conditions | AVON PROD INC (US) | 1999-06-30 | — | — | CN | claimed |
| EP-0910362-A1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1999-04-28 | — | — | EP | claimed |
| EP-0910362-B1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 2004-10-27 | — | — | EP | disclosed |
| CN-1110302-C | Oxa acids and related compounds for treating skin conditions | AVON PROD INC (US) | 2003-06-04 | — | — | CN | disclosed |
| US-6534543-B2 | Topical compositions with carboxy acid/ester, amide, or thioester/thioacid groups, with one or more of ether, amine, or sulfide groups; for example 3,6-dioxaheptanioic acid; peeling skin, softening hair | AVON PRODUCTS, INC. | 2003-03-18 | — | — | US | disclosed |
| US-20020040056-A1 | Oxa acids and related compounds for treating skin conditions | AVON PRODUCTS, INC. | 2002-04-04 | — | — | US | disclosed |
| US-6333356-B1 | TOPICAL COMPOUNDS FOR SKIN DISORDERS | AVON PRODUCTS, INC. | 2001-12-25 | — | — | US | disclosed |
| US-6069169-A | OXA acids and related compounds for treating skin conditions | AVON PRODUCTS, INC. (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0910362-A4 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 1999-12-22 | — | — | EP | disclosed |
| CN-1221342-A | Oxo acids and related compounds for the treatment of skin conditions | AVON PROD INC (US) | 1999-06-30 | — | — | CN | disclosed |
| EP-0910362-A1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1999-04-28 | — | — | EP | disclosed |
| US-5847003-A | Oxa acids and related compounds for treating skin conditions | AVON PRODUCTS, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1997046231-A1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1997-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040056-A1 | Oxa acids and related compounds for treating skin conditions | OXGR1, OXA1L, CXCR1 | GABRP 3440/4885GABRD 2491/4885GABRA1 2942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.