SCHEMBL6894560

SCHEMBL6894560

O=C(Cl)CCP(=O)(Cl)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.45
NPSR1 Q6W5P4 2/20 0.43
GAA P10253 3/20 0.42
USP2 O75604 1/20 0.42
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA5A P35218 1/20 0.40
MAPT P10636 2/20 0.39
ALPG P10696 1/20 0.39
ALOX12 P18054 1/20 0.39
NPY1R P25929 1/20 0.39
HTT P42858 1/20 0.39
NPY2R P49146 1/20 0.39
PKM P14618 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valine SCHEMBL6894558 0.84 SLC7A5 (0.41) CFTRNPSR1GAAALDH1A1MEN1
SCHEMBL11593829 0.83 KDM4E (0.37) ALDH1A1MEN1KMT2ACA2MAPT
Hydrochloric Acid SCHEMBL11592640 0.79 CFTR (0.64) CFTRNPSR1GAAUSP2ALDH1A1
SCHEMBL27532862 0.79 CFTR (0.44) CFTRNPSR1GAAUSP2ALDH1A1
SCHEMBL11418157 0.75 CFTR (0.46) CFTRNPSR1GAAUSP2ALDH1A1
SCHEMBL11592052 0.74 HPGD (0.44) CFTRALDH1A1SMN1; SMN2
SCHEMBL11590124 0.73 ACP3 (0.39) NPSR1ALDH1A1MEN1KMT2AMAPT
SCHEMBL7058667 0.71 AOX1 (0.53) CFTRNPSR1GAAUSP2ALDH1A1
SCHEMBL7058663 0.71 CFTR (0.42) CFTRNPSR1GAAUSP2ALDH1A1
SCHEMBL6572723 0.70 CFTR (0.44) CFTRNPSR1GAAUSP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1216887-C Preparation for 2-carboxyalkyl (phenyl) phosphoric acid SOLUTIA INC (US) 2005-08-31 CN claimed
EP-1099705-B1 Method for preparing 3-(hydroxyphenylphosphinyl)-propanoic acid SAEHAN IND INC (KR) 2004-02-11 EP claimed
US-6320071-B1 MIXING WATER AND FIRST REACTION MIXTURE COMPRISING PRODUCTS OF REACTION OF DICHLORO(PHENYL)PHOSPHINE AND ACRYLIC ACID OR METHACRYLIC ACID, HYDROLYZING TO PRODUCE SECOND REACTION MIXTURE COMPRISING 2-CARBOXYALKYL(PHENYL)PHOSPHINIC ACID SOLUTIA INC. 2001-11-20 US claimed
CN-1300292-A Preparation for 2-carboxyalkyl (phenyl) phosphoric acid SOLUTIA INC (US) 2001-06-20 CN claimed
EP-1099705-A1 Method for preparing 3-(hydroxyphenylphosphinyl)-propanoic acid SAEHAN INDUSTRIES, INC. (KR) 2001-05-16 EP claimed
WO-2000049025-A1 PRODUCTION OF 2-CARBOXYALKYL (PHENYL) PHOSPHINIC ACID SOLUTIA INC. (US) 2000-08-24 WO claimed
US-4081463-A Production of 2-carboxyethyl(phenyl)phosphinic acid MONSANTO COMPANY (US) 1978-03-28 US claimed
CN-1264850-C Process for preparation of 2-carboxy-alkyl (aryl) phosphonic acids and anhydrides SOLUTIA INC (US) 2006-07-19 CN disclosed
CN-1216887-C Preparation for 2-carboxyalkyl (phenyl) phosphoric acid SOLUTIA INC (US) 2005-08-31 CN disclosed
EP-1099705-B1 Method for preparing 3-(hydroxyphenylphosphinyl)-propanoic acid SAEHAN IND INC (KR) 2004-02-11 EP disclosed
CN-1474825-A Process for preparing 2-carboxy-alkyl (aryl) phosphonic acids and anhydrides 索罗蒂亚公司 2004-02-11 CN disclosed
EP-1092722-B1 Method for preparation of 3-(hydroxyphenyl phosphinyl)-propanoic acid SAEHAN IND INC (KR) 2002-09-11 EP disclosed
US-6399814-B1 ADDING WATER AT CONTROLLED SATE SOLUTIA INC. 2002-06-04 US disclosed
US-5399428-A Polyethylene terephthalate with hydroxyalkyl dicarboxylate and carboxy phosphinic acid MONSANTO COMPANY (US) 1995-03-21 US disclosed
US-4096182-A Process for the simultaneous preparation of 2,5-dioxo-1,2-oxa-phospholanes and β-halogenpropionic acid halide HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-20 US disclosed
US-4081463-A Production of 2-carboxyethyl(phenyl)phosphinic acid MONSANTO COMPANY (US) 1978-03-28 US disclosed
US-4081463-A Production of 2-carboxyethyl(phenyl)phosphinic acid MONSANTO COMPANY (US) 1978-03-28 US disclosed
US-4062888-A Continuous production of 2,5-dioxo-1-oxa-2-phospholanes HOECHST AKTIENGESELLSCHAFT (DT) 1977-12-13 US disclosed
US-4045480-A Process for preparing 1,2-oxa-phospholanes HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-30 US disclosed
US-4022826-A DIHALOGEN-PHOSPHINES, ACRYLIC-METHACRYLIC-CROTONIC ACID HOECHST AKTIENGESELLSCHAFT (DT) 1977-05-10 US disclosed