Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003199 | 0.77 | POLB (0.46) | FABP3FABP4POLBFABP5KIF11 | |
| SCHEMBL8017724 | 0.77 | FABP4 (0.67) | FABP3FABP4POLBFABP5KIF11 | |
| SCHEMBL1003689 | 0.75 | TSHR (0.43) | POLBMAP2K1CA2CA1CA9 | |
| SCHEMBL3339816 | 0.75 | POLB (0.42) | POLBALOX5KIF11CA2CA12 | |
| SCHEMBL12545597 | 0.71 | FABP3 (0.43) | FABP3FABP4POLBFABP5KIF11 | |
| SCHEMBL1005467 | 0.71 | FABP3 (0.43) | FABP3FABP4POLBFABP5KIF11 | |
| SCHEMBL6894637 | 0.71 | PARP1 (0.43) | MAP2K1KIF11HTTTSHRAPOBEC3A | |
| SCHEMBL28014363 | 0.71 | FABP3 (0.58) | FABP3FABP4POLBFABP5GAA | |
| SCHEMBL25556183 | 0.71 | POLB (0.49) | POLBALOX5KIF11HTTNPC1 | |
| SCHEMBL1091699 | 0.70 | GAA (0.50) | FABP3FABP4POLBP2RX4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |