Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.67 |
| ▸ | FABP3 | P05413 | 2/20 | 0.67 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014363 | 0.88 | FABP3 (0.58) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL28348175 | 0.81 | GABRA1 (0.54) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL2383444 | 0.80 | FABP4 (0.69) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL446680 | 0.80 | FABP4 (0.69) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL810177 | 0.80 | FABP3 (1.00) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL10167825 | 0.79 | FABP3 (0.62) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL17311830 | 0.78 | FABP3 (0.96) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL7484474 | 0.78 | FABP4 (0.67) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL14519841 | 0.78 | FABP4 (0.67) | FABP4FABP3FABP5GABRA1GABRB2 | |
| SCHEMBL1003199 | 0.78 | POLB (0.46) | FABP4FABP3FABP5GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150385-A | VIRICIDE WITH ACTIVITY AGAINST CYTOMEGALO VIRUS (CMV), HERPES VIRUS INCLUDING VARICELLA ZOSTER VIRUS, THE EPSTEIN-BARR VIRUS, THE HERPES SIMPLEX VIRUS, AND THE HUMAN HERPES VIRUS TYPE 8 (HHV-8) | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-21 | — | — | US | disclosed |