Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tert-Butylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 3/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL4367430 | 0.90 | TSHR (0.69) | TSHRHPGDALDH1A1TP53HIF1A | |
| Chloromethane SCHEMBL8216104 | 0.90 | TSHR (0.69) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL14982 | 0.89 | — | — | |
| SCHEMBL30074662 | 0.89 | TSHR (0.75) | TSHRHPGDALDH1A1TP53HIF1A | |
| Ethylamine SCHEMBL4372163 | 0.88 | TSHR (0.67) | TSHRHPGDALDH1A1TP53HIF1A | |
| Methylamine SCHEMBL28257768 | 0.88 | TSHR (0.67) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL2546168 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL22686891 | 0.87 | — | — | |
| Hydrogen Sulfide SCHEMBL12537994 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL15846411 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102380257-B | Desalination filter material | IND TECH RES INST | 2013-11-06 | — | — | CN | claimed |
| CN-105050705-B | The microcapsules of spray drying | 恩盖普有限公司 | 2018-07-27 | — | — | CN | disclosed |
| CN-102380257-B | Desalination filter material | IND TECH RES INST | 2013-11-06 | — | — | CN | disclosed |
| CN-1611533-B | Antistatic resin composition | SANYO CHEMICAL IND LTD | 2010-05-05 | — | — | CN | disclosed |
| CN-1611533-A | Antistatic resin composition | SANYO CHEM IND CO LTD (JP) | 2005-05-04 | — | — | CN | disclosed |
| US-6734244-B2 | POLYMER COMPRISING ONE OR MORE MONOMERS HAVING STERICALLY HINDERED SECONDARY AMINE AND A CARBOXYLIC ACID MONOMER | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION | 2004-05-11 | — | — | US | disclosed |
| US-20040048964-A1 | COATING COMPOSITION FOR INKJET APPLICATIONS | CELANESE INTERNATIONAL CORPORATION | 2004-03-11 | — | — | US | disclosed |
| CN-1446360-A | Cable or cable component coated with a water swellable material | DUSSEK CAMPBELL CABLES LTD (GB) | 2003-10-01 | — | — | CN | disclosed |
| US-6313224-B1 | FOR MULTILAYER POWDER COATINGS | PPG INDUSTRIAL OHIO, INC. | 2001-11-06 | — | — | US | disclosed |
| EP-0880565-B1 | COATING COMPOSITIONS WITH FLOW MODIFIERS AND THE FLOW MODIFIERS AND MULTILAYERED COATINGS | PPG IND OHIO INC (US) | 1999-09-29 | — | — | EP | disclosed |
| US-4933170-A | POLYMER OF VINYL ACETATE OR PROPIONATE, VINYL ESTER OF A BRANCHED CARBOXY ACID AND A MONOALKYL MALEATE NEUTRALIZED WITH SODIUM OR POTASSIUM HYDROXIDE | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0370338-A1 | Improved hair fixative compositions containing alpha-aminomethylene phosphonate betaines | National Starch and Chemical Investment Holding Corporation (US) | 1990-05-30 | — | — | EP | disclosed |
| US-4923695-A | VINYL ESTER-MONOALKYL MALEATE INTERPOLYMER | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0364887-A2 | High hydrocarbon tolerant hair fixing compositions having superior shampoo removability | National Starch and Chemical Corporation (US) | 1990-04-25 | — | — | EP | disclosed |
| EP-0331994-A2 | Hydrocarbon tolerant hair fixing compositions | National Starch and Chemical Corporation (US) | 1989-09-13 | — | — | EP | disclosed |
| US-4859455-A | Hydrocarbon tolerant hair fixing compositions | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |
| US-4842852-A | HALOGEN-FREE PROPELLANTS; NEUTRALIZED ACRYLATE BASED POLYMERS | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0203372-B1 | PROCESS FOR MAKING PHOTOPOLYMERIZABLE AROMATIC POLYAMIC ACID DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-26 | — | — | EP | disclosed |
| EP-0203372-A2 | Process for making photopolymerizable aromatic polyamic acid derivatives | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-12-03 | — | — | EP | disclosed |
| US-4551522-A | Process for making photopolymerizable aromatic polyamic acid derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-05 | — | — | US | disclosed |