SCHEMBL6894738

SCHEMBL6894738

CC(O)(C=O)CCOP(=O)(O)C(F)(F)P(=O)(O)O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MVD P53602 1/20 0.34
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6899470 0.84 PGK1 (0.35) MVDPGK1PGK2LMNA
SCHEMBL6897790 0.80 PGK1 (0.32) MVDPGK1PGK2LMNA
SCHEMBL6898819 0.79 PGK1 (0.31) MVDPGK1PGK2
SCHEMBL6896592 0.79 PGK1 (0.31) MVDPGK1PGK2
SCHEMBL6896792 0.79 PGK1 (0.35) MVDPGK1PGK2
SCHEMBL6900167 0.73 PGK1 (0.43) PGK1PGK2LMNA
SCHEMBL6902057 0.69 BTN3A1 (0.56)
SCHEMBL11952599 0.67 PTPN1 (0.33)
SCHEMBL26250157 0.65 LMNA (0.41) PGK1PGK2LMNA
SCHEMBL16021681 0.63 LMNA (0.32) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1165573-B1 COMPOUNDS SELECTIVELY INHIBITING GAMMA 9 DELTA 2 T LYMPHOCYTES INST NAT SANTE ETDE LA RECH ME (FR) 2004-01-21 EP disclosed
US-20040009123-A1 Compounds selectively inhibiting gamma 9 delta 2 T lymphocytes INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2004-01-15 US disclosed
US-20040006131-A1 Compounds selectively inhibiting gamma 9 delta 2 T lymphocytes INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2004-01-08 US disclosed
US-6624151-B1 Concerns the uses of said compounds as selective inhibitors of T gamma 9 delta 2 lymphocytes, their uses, for therapeutic purposes. INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2003-09-23 US disclosed
EP-1165573-A1 COMPOUNDS SELECTIVELY INHIBITING GAMMA 9 DELTA 2 T LYMPHOCYTES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2002-01-02 EP disclosed
WO-2000059916-A1 COMPOUNDS SELECTIVELY INHIBITING GAMMA 9 DELTA 2 T LYMPHOCYTES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2000-10-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040006131-A1 Compounds selectively inhibiting gamma 9 delta 2 T lymphocytes CD4, IL2RA, CD74 MVD 1429/4885PGK1 1638/4885PGK2 1473/4885
US-20040009123-A1 Compounds selectively inhibiting gamma 9 delta 2 T lymphocytes CD4, IL2RA, CD74 MVD 1429/4885PGK1 1638/4885PGK2 1473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.