Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898328 | 0.80 | FDPS (0.46) | FDPSGRM4LMNA | |
| SCHEMBL6892102 | 0.79 | FDPS (0.45) | FDPSGRM4LMNA | |
| SCHEMBL6893873 | 0.79 | FDPS (0.45) | FDPSGRM4LMNA | |
| SCHEMBL6894688 | 0.79 | FDPS (0.45) | FDPSGRM4LMNA | |
| SCHEMBL6897050 | 0.79 | FDPS (0.45) | FDPSGRM4LMNA | |
| SCHEMBL10785210 | 0.73 | FDPS (0.67) | FDPS | |
| SCHEMBL10257119 | 0.71 | ALDH1A1 (0.53) | ALDH1A1 | |
| SCHEMBL10263719 | 0.70 | SMPD1 (0.36) | FDPSALDH1A1 | |
| SCHEMBL10654239 | 0.70 | FDPS (0.44) | FDPSLMNA | |
| SCHEMBL4095556 | 0.69 | FDPS (1.00) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165573-B1 | COMPOUNDS SELECTIVELY INHIBITING GAMMA 9 DELTA 2 T LYMPHOCYTES | INST NAT SANTE ETDE LA RECH ME (FR) | 2004-01-21 | — | — | EP | disclosed |
| US-20040009123-A1 | Compounds selectively inhibiting gamma 9 delta 2 T lymphocytes | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2004-01-15 | — | — | US | disclosed |
| US-20040006131-A1 | Compounds selectively inhibiting gamma 9 delta 2 T lymphocytes | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2004-01-08 | — | — | US | disclosed |
| US-6624151-B1 | Concerns the uses of said compounds as selective inhibitors of T gamma 9 delta 2 lymphocytes, their uses, for therapeutic purposes. | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2003-09-23 | — | — | US | disclosed |
| EP-1165573-A1 | COMPOUNDS SELECTIVELY INHIBITING GAMMA 9 DELTA 2 T LYMPHOCYTES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059916-A1 | COMPOUNDS SELECTIVELY INHIBITING GAMMA 9 DELTA 2 T LYMPHOCYTES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2000-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006131-A1 | Compounds selectively inhibiting gamma 9 delta 2 T lymphocytes | CD4, IL2RA, CD74 | FDPS 2429/4885ALDH1A1 47/4885GRM4 4334/4885 |
| US-20040009123-A1 | Compounds selectively inhibiting gamma 9 delta 2 T lymphocytes | CD4, IL2RA, CD74 | FDPS 2429/4885ALDH1A1 47/4885GRM4 4334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.