SCHEMBL68948

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10765390	0.82	ALOX15 (0.39)	POLBALDH1A1HTTALOX15ALOX12
	SCHEMBL604518	0.78	POLB (0.50)	POLBCSNK2A1KDM4EALDH1A1GAA
	SCHEMBL31392373	0.78	POLB (0.50)	POLBCSNK2A1KDM4EALDH1A1GAA
	SCHEMBL10889720	0.76	POLB (0.34)	POLBGAAALOX15ALOX12SMN1; SMN2
	SCHEMBL5700724	0.72	ESR1 (0.50)	ESR1ESR2
	SCHEMBL30081125	0.69	POLB (0.56)	POLBCSNK2A1KDM4EALDH1A1GAA
	SCHEMBL2367630	0.69	POLB (0.56)	POLBCSNK2A1KDM4EALDH1A1GAA
	SCHEMBL2101837	0.69	POLB (0.39)	POLBCSNK2A1KDM4EALDH1A1GAA
	SCHEMBL6027732	0.68	ESR2 (0.40)	POLBCSNK2A1KDM4EALDH1A1GAA
	SCHEMBL25414587	0.67	ALOX15 (0.43)	POLBCSNK2A1KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.