SCHEMBL5700724

SCHEMBL5700724

Oc1ccc(Oc2ccc(O)c(Br)c2Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.50
ESR2 Q92731 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
LTA4H P09960 3/20 0.43
NR1H2 P55055 1/20 0.43
BAX Q07812 1/20 0.43
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41
TAAR5 O14804 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
PARP10 Q53GL7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10765390 0.83 ALOX15 (0.39) MEN1KMT2A
SCHEMBL10766889 0.74 MEN1 (0.48) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL9623605 0.73 MEN1 (0.52) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL676467 0.72 MEN1 (0.56) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL2711865 0.72 MEN1 (0.56) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL14645135 0.72 MEN1 (0.50) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL11307521 0.72 MEN1 (0.50) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL9623381 0.72 MEN1 (0.50) ESR1ESR2MEN1KMT2ALTA4H
SCHEMBL68948 0.72 POLB (0.41) ESR1ESR2
SCHEMBL3175106 0.69 ESR2 (1.00) ESR1ESR2MEN1KMT2ALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140827-B1 SYNTHESIS OF PHENOLIC MONOMERS CONTAINING IMIDE OR DIIMIDE MOIETIES AND HIGH HEAT CARBONATE POLYMERS PREPARED THEREFROM GEN ELECTRIC (US) 2006-07-26 EP disclosed
EP-1140827-A1 SYNTHESIS OF PHENOLIC MONOMERS CONTAINING IMIDE OR DIIMIDE MOIETIES AND HIGH HEAT CARBONATE POLYMERS PREPARED THEREFROM GENERAL ELECTRIC COMPANY (US) 2001-10-10 EP disclosed
US-6096853-A Synthesis of phenolic monomers containing imide or diimide moieties and high heat carbonate polymers prepared therefrom GENERAL ELECTRIC COMPANY (US) 2000-08-01 US disclosed
WO-2000037442-A1 SYNTHESIS OF PHENOLIC MONOMERS CONTAINING IMIDE OR DIIMIDE MOIETIES AND HIGH HEAT CARBONATE POLYMERS PREPARED THEREFROM GENERAL ELECTRIC COMPANY (US) 2000-06-29 WO disclosed
US-5965688-A FORMING AN ALIPHATIC CHLOROFORMATE AND THEN REACTING THE BISCHLOROFORMATE WITH AROMATIC DIOL IN AN INTERFACIAL POLYMERIZATION REACTION TO FORM A COPOLYCARBONATE GENERAL ELECTRIC COMPANY (US) 1999-10-12 US disclosed
EP-0922722-A1 Interfacial polycarbonate polymerization process and product GENERAL ELECTRIC COMPANY (US) 1999-06-16 EP disclosed
EP-0382800-A1 IMPACT MODIFIED POLYAMIDE/AROMATIC POLYCARBONATE BLENDS GENERAL ELECTRIC COMPANY (US) 1990-08-22 EP disclosed
WO-1990002156-A1 IMPACT MODIFIED POLYAMIDE/AROMATIC POLYCARBONATE BLENDS GENERAL ELECTRIC COMPANY (US) 1990-03-08 WO disclosed