Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 5/20 | 0.41 |
| ▸ | CTSD | P07339 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352714 | 1.00 | MLYCD (0.49) | MLYCDTP53HPGDEGFRERBB2 | |
| SCHEMBL6139506 | 0.93 | MLYCD (0.44) | MLYCDTP53HPGDEGFRERBB2 | |
| SCHEMBL5130313 | 0.93 | MLYCD (0.44) | MLYCDTP53HPGDEGFRERBB2 | |
| SCHEMBL3349246 | 0.89 | KDM4E (0.45) | MLYCDTP53HPGDEGFRERBB2 | |
| SCHEMBL6886635 | 0.86 | MLYCD (0.39) | MLYCDTP53HPGDEGFRERBB2 | |
| SCHEMBL7055563 | 0.86 | DHODH (0.56) | MLYCDTP53HPGDGABRA1GABRB2 | |
| SCHEMBL2206850 | 0.86 | TP53 (0.51) | MLYCDTP53HPGDEGFRERBB2 | |
| SCHEMBL6894254 | 0.85 | MLYCD (0.38) | MLYCDTP53HPGDEGFRERBB2 | |
| SCHEMBL3355469 | 0.85 | TP53 (0.41) | MLYCDTP53HPGDEGFRERBB2 | |
| SCHEMBL28278838 | 0.85 | MLYCD (0.62) | MLYCDTP53HPGDEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |