Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LIG1 | P18858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849708 | 0.85 | ALDH1A1 (0.55) | DAOALDH1A1LMNAPRNPRECQL | |
| SCHEMBL1401537 | 0.83 | DAO (0.50) | DAOALDH1A1LMNAPRNPRECQL | |
| SCHEMBL14942670 | 0.82 | DAO (0.46) | DAOALDH1A1LMNAPRNPRECQL | |
| SCHEMBL15521803 | 0.82 | DAO (0.45) | DAOALDH1A1LMNAPRNPRECQL | |
| SCHEMBL2409099 | 0.82 | ALDH1A1 (0.47) | DAOALDH1A1LMNAPRNPRECQL | |
| SCHEMBL4058053 | 0.82 | ALDH1A1 (0.60) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL8794696 | 0.82 | DAO (0.50) | DAOALDH1A1LMNAPRNPRECQL | |
| SCHEMBL7644385 | 0.82 | DAO (0.50) | DAOALDH1A1LMNAPRNPRECQL | |
| SCHEMBL262537 | 0.82 | DAO (0.50) | DAOALDH1A1LMNAPRNPRECQL | |
| SCHEMBL1368290 | 0.81 | NPSR1 (0.50) | ALDH1A1LMNAPRNPRECQLRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793250-A | Heteroaryl derivatives for the treatment of respiratory diseases | 奇斯药制品公司 | 2016-07-20 | — | — | CN | disclosed |
| US-20040082079-A1 | Low affinity screening method | GRAFFINITY PHARMACEUTICALS AG. (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1360489-A1 | LOW AFFINITY SCREENING METHOD | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002063299-A1 | LOW AFFINITY SCREENING METHOD | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-08-15 | — | — | WO | disclosed |