Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PRNP | P04156 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894878 | 0.85 | DAO (0.47) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL8971725 | 0.84 | POLB (0.59) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL8971941 | 0.84 | POLB (0.59) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL6653369 | 0.84 | POLB (0.59) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL6981207 | 0.83 | HPGD (0.57) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| Hydrochloric Acid SCHEMBL8998499 | 0.83 | POLB (0.57) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| Hydrochloric Acid SCHEMBL8998584 | 0.83 | POLB (0.57) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL846642 | 0.82 | POLB (0.56) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL2162982 | 0.81 | HPGD (0.55) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL4197232 | 0.81 | ALDH1A1 (0.51) | ALDH1A1LMNAPRNPRECQLRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415510-A2 | L-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1991-03-06 | — | — | EP | disclosed |
| US-4920125-A | L-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1990-04-24 | — | — | US | disclosed |