Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.77 |
| ▸ | PPARD | Q03181 | 1/20 | 0.77 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.77 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ZDHHC7 | Q9NXF8 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621074 | 1.00 | LCK (0.77) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL7658440 | 1.00 | LCK (0.77) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL22826569 | 1.00 | LCK (0.77) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL688574 | 1.00 | LCK (0.77) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL689632 | 1.00 | LCK (0.77) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL1449604 | 0.97 | LCK (0.73) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL2122342 | 0.91 | LCK (0.65) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL29196173 | 0.90 | LCK (0.65) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL22814782 | 0.90 | LCK (0.65) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL10736739 | 0.90 | LCK (0.65) | LCKPPARDZDHHC20ZDHHC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279978-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING ALPHA-HALOGENATED DICARBOXYLIC ACIDS | Epis S.A. (CH) | 1992-01-02 | — | — | EP | claimed |
| US-8222446-B2 | Method for producing dihydroxybenzene derivative | MITSUI CHEMICALS, INC. (JP) | 2012-07-17 | — | — | US | disclosed |
| EP-1820667-B1 | PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-20110004013-A1 | METHOD FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE | MITSUI CHEMICALS, INC. (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2269976-A1 | PROCESS FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE | Mitsui Chemicals, Inc. (JP) | 2011-01-05 | — | — | EP | disclosed |
| US-7823614-B2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2010-11-02 | — | — | US | disclosed |
| US-20090229728-A1 | PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1820667-A1 | PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110004013-A1 | METHOD FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE | UBE2B, UBE2G2, TUBB2B | LCK 1463/4885PPARD 2623/4885ZDHHC20 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.